Drug Interaction: Dextromethorphan is known to interact with other drugs like abiraterone acetate, amiodarone (HCl), fluoxetine (HCl), haloperidol, mitomycin C, moclobemide, paroxetine, phenelzine, propafenone (HCl), quinidine, sibutramine. Always consult your physician for the change of dose regimen or an alternative drug of choice that may strictly be required.
Mechanism of Action: Dextromethorphan is an opioid-like drug that binds to and acts as antagonist to the NMDA glutamatergic receptor, it is an agonist to the opioid sigma 1 and sigma 2 receptors, it is also an alpha3/beta4 nicotinic receptor antagonist and targets the serotonin reuptake pump. Dextromethorphan is rapidly absorbed from the gastrointestinal tract, where it enters the bloodstream and crosses the blood-brain barrier.
Pregnancy Impact: Animal reproduction studies have shown an adverse effect on the fetus and there are no adequate and well-controlled studies in humans, but potential benefits may warrant use of the drug in pregnant women despite potential risks.
Impact During Lactation: There are no controlled studies in breastfeeding women, however the risk of untoward effects to a breastfed infant is possible; or, controlled studies show only minimal non-threatening adverse effects. Drugs should be given only if the potential benefit justifies the potential risk to the infant.
Price of Benadryl Syrup 50 Ml : Rs.39.00
Dextromethorphan 15 mg
Johnson & Johnson
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Benadryl Syrup 50 Ml Reviews
best for cough nd sore throat Review by bhavesh
I hev been using dis syrup from past 15 yrs everytime any one in my family needs something or cough....to my happiness nd thanks for bigchemist for giving addtional discount (Posted on 11/4/2015)
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