Brufen (200Mg) contains following Salts:-
Ibuprofen - Drug Information
Indications Ibuprofen is primarily indicated in conditions like Cystic fibrosis, Fever, Juvenile chronic arthritis, Migraine, Mild to moderate pain, Musculoskeletal pain, Nausea and vomiting (palliative care), Osteoarthritis, Pain, Post operative analgesia, Rheumatoid arthritis, Severe pain and tenderness in benign fibrocystic breast disease, Toothache, and can also be given in adjunctive therapy as an alternative drug of choice in Acute arthritis, Ankylosing spondylitis, Dysmenorrhoea, Inflammatory bowel disease.
Dosage Adult: PO Rheumatoid arthritis; Osteoarthritis 400-800 mg 3-4 times/day. Max: 3.2 g/day. Mild to moderate pain; Dysmenorrhoea; Fever 200-400 mg 4-6 hrly. Max: 1.2 g daily. IV Pain relief 400-800 mg 6 hrly, as needed. Max: 3.2 g/day. Fever Initially, 400 mg followed by 400 mg 4-6 hrly, or 100-200 mg 4 hrly. Max: 3.2 g/day. Topical/Cutaneous Pain and inflammation associated w/ musculoskeletal and joint disorders As 5% cream, foam, gel, spray soln or 10% gel: Apply as directed.
Contra-Indications Hypersensitivity. Treatment of perioperative pain in the setting of CABG surgery. Patient whom asthma, urticaria or other allergic-type reaction are precipitated by aspirin or other NSAIDs. Active or history of peptic ulcer; history of GI bleeding. Neonates w/ congenital heart disease, suspected necrotising enterocolitis, and impaired renal function. 3rd trimester of pregnancy, and lactation.
Side Effects Indigestion, Vomiting, Abdominal Pain, Heart Burn, Diarrhea, Dizziness, Skin Rashes, Sever Allergic Reactions. Heart Patients May Experience Swelling Of Body And Fluid Retention. Overdose May Cause Stomach Or Abdominal Pain And Ringing In The Ears
Special Precautions Bleeding disorders, CV disease. Infants w/ increased total bilirubin. Premature neonates w/ existing or at risk of infection. Hepatic and renal impairment. Elderly (avoid chronic use). Monitoring Parameters Monitor CBC, occult blood loss, hepatic and renal function.
Drug-Interaction Increased risk of GI bleeding w/ warfarin, corticosteroids, SSRIs and aspirin. May reduce the natriuretic effects of diuretics. Reduced antihypertensive effect of ACE inhibitors and angiotensin II receptor antagonists. May increase toxicity of lithium and methotrexate. Increased nephrotoxicity w/ ciclosporin and tacrolimus.
Tizanidine - Drug Information
Typical usage: :Cerebral palsy, cerebrovascular accident, myelopathy, nausea and vomiting (acute attacks), sclerosis, spasticity, spastiicity associated with multiple sclerosis.
Probable Side Effects: :Dizziness, drowsiness, fatigue, nausea, insomnia, dry mouth, hallucination, muscle weakness, somnolence, GI disturbance.
Drug Interaction: Tizanidine is known to interact with other drugs like alcohol, diazoxide, digoxin, fosphenytoin. Always consult your physician for the change of dose regimen or an alternative drug of choice that may strictly be required.
Mechanism of Action: Tizanidine reduces spasticity by increasing presynaptic inhibition of motor neurons through agonist action at a2-adrenergic receptor sites.
Pregnancy Impact: Animal reproduction studies have shown an adverse effect on the fetus and there are no adequate and well-controlled studies in humans, but potential benefits may warrant use of the drug in pregnant women despite potential risks.
Impact During Lactation: There are no controlled studies in breastfeeding women, however the risk of untoward effects to a breastfed infant is possible; or, controlled studies show only minimal non-threatening adverse effects. Drugs should be given only if the potential benefit justifies the potential risk to the infant.
Price of Brufen (200Mg) : Rs.5.00
|Dispatches by||Next Day|
|Composition||Ibuprofen 200 mg, Tizanidine 2 mg|
|Salt Information||Ibuprofen, Tizanidine|
|Pack Size||15 Tablet|
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Substitutes of Brufen (200Mg)
Rs.1.00Cyper Drugs & Pharma
Rs.1.00Orchid Chemicals & Pharma
Rs.1.00Low Cost Standard Therapeutics (Locost)
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