Calaptin Sr 240mg 10Tablet contains following Salts:-
Verapamil - Drug Information
Indications Verapamil is primarily indicated in conditions like Angina, Cardiac arrhythmia, Hypertension, Ischaemic heart disease, Paroxysmal tachyarrhythmias, Supraventricular arrhythmias, Supraventricular tachycardia, and can also be given in adjunctive therapy as an alternative drug of choice in Cardiomyopathy, Migraine, Psychosis, Pulmonary hypertension.
Dosage Adult: PO Supraventricular arrhythmias 120-480 mg/day in 3-4 divided doses. Angina pectoris 120 mg 3 times/day. Extended release Up to 480 mg/day. HTN 240 mg/day in 2-3 divided doses. Max: 480 mg/day. IV Supraventricular arrhythmias Initial: 5-10 mg, may give 10 mg 30 mins after initial dose, if needed
Contra-Indications Cardiogenic shock, severe bradycardia, severe left ventricular dysfunction, uncompensated heart failure, hypotension (systolic pressure <90 mm Hg), porphyria. Patients with atrial flutter or atrial fibrillation and an accessory bypass tract (e.g., Wolff-Parkinson-White, Lown-Ganong-Levine syndromes). 2nd or 3rd degree AV block (unless pacemaker is fitted).
Side Effects Hepatotoxicity, Impotence, Mental Confusion, Hyperprolactinemia, Myoclonic Dystonia, Dizziness, Headache, Fatigue, Nausea, Palpitation, Constipation, Flushing.
Special Precautions 1st degree AV block. Hypertrophic cardiomyopathy, patients with decreased neuromuscular transmission. Bradycardia or conduction disturbances. Hepatic or renal impairment. For IV admin, verapamil to be given slowly under continuous ECG and BP monitoring. Conventional tablets, extended-release capsules, extended-release core tablets, and controlled extended-release capsules can be admin without regard to food while extended-release tablets to be admin with food. Slower infusion rates (over >3 min) in elderly. Periodic monitoring of LFT during long-term therapy. Avoid sudden withdrawal. Infants and neonates, elderly. Pregnancy and lactation.
Drug-Interaction Increased cardiac depressant effects with ?-blockers and flecainide. Increased risk of additive bradycardia, conduction disturbances and digoxin toxicity with digoxin. Increased risk of bradycardia and hypotension with remifentanil and sufentanil. Increased levels of both everolimus and verapamil on concurrent use. May increase doxorubicin, buspirone, carbamazepine, ciclosporin, epirubicin, eplerenone, quinidine, statins, sirolimus, tacrolimus, quinupristin/dalfopristin levels. Verapamil increase blood alcohol levels. Unpredictable interactions with lithium. Decreased verapamil concentrations with phenobarbital, sulfinpyrazone, rifampicin, rifabutin and rifapentine. Increased verapamil concentrations with protease inhibitors and cimetidine.Increased cardiac depressant effects with amiodarone. Increased risk of QT prolongation with dofetilide, ranolazine, sertindole. Additive bradycardia with ivabradine. Increased risk of heart block with clonidine. Increased risk of acute hyperkalaemia and CV collapse with dantrolene.
Price of Calaptin Sr 240mg 10Tablet : Rs.52.00
|Dispatches by||Next Day|
|Composition||Verapamil 240 mg|
|Pack Size||10 Tablet|
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Substitutes of Calaptin Sr 240mg 10Tablet
Rs.1.00Cyper Drugs & Pharma
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Rs.1.00Low Cost Standard Therapeutics (Locost)
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