Cardasol 150mg injection 3ml contains following Salts:-
Amiodarone - Drug Information
Indications Amiodarone is primarily indicated in conditions like Angina pectoris, Atrial fibrillation, Atrial flutter, Ectopic tachycardia, Hypertrophic cardiomyopathy, Mild to moderate dementia in alzheimer"s disease, Paroxysmal re-entry av tachycardia,Paroxysmal supraventricular tachycardia, Paroxysmal ventricular tachycardia, Pituitary desensitisation, Tobacco amblyopia and leber"s optic atrophy, Ventricular fibrillation,Ventricular fibrillation, pulseless ventricular tachycardia, and can also be given in adjunctive therapy as an alternative drug of choice in Treatment of arrhythmias.
Dosage Adult: PO Ventricular arrhythmias 800-1,600 mg/day for 1-3 wk until response achieved, then reduce dose to 600-800 mg/day for 1 mth. Maintenance: 400 mg/day. IV Life-threatening ventricular arrhythmias Recommended starting dose: About 1 g over 1st 24 hr; dose is given in a 3-phase sequence: Initial rapid loading dose followed by slow loading phase, then first maintenance phase. After the 1st 24 hr, maintain infusion at 0.5 mg/min; for breakthrough episodes, supplemental doses of 150 mg may be given; may repeat supplemental doses up to a max IV dose of 2.2 g/24 hr. May continue maintenance infusion for up to 2-3 wk with caution. Conversion to PO depends on the administered IV dose and bioavailability of the oral drug. Pulseless ventricular fibrillation or ventricular tachycardia Initial: 300 mg as a single dose by rapid inj if VF or VT recurs. Supplemental dose: 150 mg, followed by an infusion of 1 mg/min for 6 hr, then 0.5 mg/min.
Contra-Indications Hypersensitivity to amiodarone or iodine. Severe sinus node dysfunction, 2nd and 3rd degree heart block (except in patients with a functioning artificial pacemaker), cardiogenic shock, pregnancy.
Side Effects Neuropathy, Thyroid Disorders, Alopecia, Skin Reactions, Sleep Disturbances, GI Reactions, Visual Disorders.
Special Precautions Close monitoring is recommended as amiodarone may worsen arrhythmia especially when used concurrently with other anti-arrhythmic drugs or drugs that prolong QT interval. May cause hypotension and bradycardia. May increase risk of liver toxicity. May cause visual disturbance/impairment; corneal refractive laser surgery is not recommended in patients on amiodarone treatment. May cause lung damage; monitor for pulmonary toxicity e.g. acute respiratory distress syndrome. Monitor liver functions regularly. May affect defibrillation or pacing thresholds of cardiac devices. Correct electrolyte imbalance before starting treatment. Caution when used in patients undergoing surgery. Avoid excessive sunlight exposure due to increased risk of photosensitivity. Hepatic impairment, thyroid disease, elderly. Lactation
Drug-Interaction Potentiation of antiarrhythmic drugs. Possible increased risk of adverse effects when used with anaesthetic agents. Monitor plasma levels of amiodarone when used with HIV protease inhibitors. Cimetidine may increase serum levels of amiodarone. Concurrent use may increase serum levels of ciclosporin. May increase risk of myopathy or rhabdomyolysis when used with HMG-CoA reductase inhibitors. Rifampin may reduce the serum levels of amiodarone.Potentially Fatal: Potentiates the effect of warfarin and other anticoagulants hence dose of warfarin generally needs to be reduced approx half. Raised plasma concentrations of digoxin, phenytoin and quinidine. Additive effect with beta-blockers and calcium-channel blockers (e.g. verapamil and diltiazem).
Price of Cardasol 150mg injection 3ml : Rs.136.00
|Dispatches by||Next Day|
|Composition||Amiodarone 50 mg|
|Brand Name||Shree Ganesh Pharma|
|Pack Size||3 ml|
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