Cardules Plus 20mg 10Tablet contains following Salts:-
Atenolol - Drug Information
Typical usage: :Hypertension, angina pectoris. Cardiac arrhythmias. Migraine prophylaxis.
Probable Side Effects: :Bronchospasm; cold extremities, fatigue, dizziness, insomnia, lethargy, confusion, headache, depression, nightmares, nausea, diarrhoea, constipation, impotence and paraesthesia. Potentially Fatal: Heart failure, 2nd or 3rd degree AV block.
Drug Interaction: Calcium channel blockers and digoxin can cause lowering of blood pressure and heart rate to dangerous levels when administered together with atenolol. Atenolol can mask the early warning symptoms of low blood sugar (hypoglycemia), and should be used with caution in patients receiving treatment for diabetes.
Mechanism of Action: Atenolol is a competitive cardioselective ?1-blocker. It does not have effect on ?2-receptors except in high doses. Its cardioselectivity is dose-related. Atenolol reduces resting and exercise-induced heart rate as well as myocardial contractility. Peripheral ?-blockade may result in vasoconstriction. Atenolol reduces BP and heart rate which results in reduced myocardial work and O2 requirement leading to improved exercise tolerance and reduced frequency and intensity of anginal attack.
Pregnancy Impact: There is positive evidence of human fetal risk based on adverse reaction data from investigational or marketing experience or studies in humans, but potential benefits may warrant use of the drug in pregnant women despite potential risks.
Impact During Lactation: There is positive evidence of risk to a breastfed infant or to breastmilk production, but the benefits of use in breastfeeding mothers may be acceptable despite the risk to the infant (e.g. if the drug is needed in a life-threatening situation or for a serious disease for which safer drugs cannot be used or are ineffective).
Atorvastatin - Drug Information
Typical usage: :Familial hypercholesterolaemia, homozygous familial hypercholesterolemia, hypercholesterolaemia, hyperlipoproteinaemia, hypertriglyceridaemia.
Probable Side Effects: :Flatulence, weakness, headache, diarrhea, fever, myalgia, constipation, insomnia, abdominal pain, skin rashes, blurred vision, pharyngitis, dyspepsia, malaise, asthenia, arthralgia, elevation of liver enzymes, myopathy, backache, increased intracranial pressure, GI disturbance, sinusitis.
Drug Interaction: Atorvastatin is known to interact with other drugs like aliskiren, amprenavir, cimetidine (HCl), colestipol (HCl), cyclosporin A, digoxin, erythromycin, mibefradil (Di HCl), nicotinic acid, repaglinide, warfarin (Na). Always consult your physician for the change of dose regimen or an alternative drug of choice that may strictly be required.
Mechanism of Action: Atorvastatin selectively and competitively inhibits the hepatic enzyme HMG-CoA reductase. As HMG-CoA reductase is responsible for converting HMG-CoA to mevalonate in the cholesterol biosynthesis pathway, this results in a subsequent decrease in hepatic cholesterol levels.
Pregnancy Impact: Studies in animals or humans have demonstrated fetal abnormalities and/or there is positive evidence of human fetal risk based on adverse reaction data from investigational or marketing experience, and the risks involved in use of the drug in pregnant women clearly outweigh potential benefits.
Impact During Lactation: Studies in breastfeeding mothers have demonstrated that there is significant and documented risk to the infant based on human experience, or it is a medication that has a high risk of causing significant damage to an infant. The risk of using the drug in breastfeeding women clearly outweighs any possible benefit from breastfeeding. The drug is contraindicated in women who are breastfeeding an infant.
Price of Cardules Plus 20mg 10Tablet : Rs.53.00
|Dispatches by||Next Day|
|Composition||Atenolol 50 mg, Atorvastatin 20 mg|
|Salt Information||Atenolol, Atorvastatin|
|Pack Size||10 Tablet|
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Substitutes of Cardules Plus 20mg 10Tablet
Rs.1.00Cyper Drugs & Pharma
Rs.1.00Orchid Chemicals & Pharma
Rs.1.00Low Cost Standard Therapeutics (Locost)
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