Typical usage: :Inoperable metastatic breast cancer, muscle weakness.
Probable Side Effects: :Increased vascularity of the skin, hypercalcaemia, impaired glucose tolerance, increased bone growth and skeletal weight, increase LDL cholesterol, increase haematocrit and fibrinolytic activity, headache, depression and GI bleeding, males: spermatogenesis suppression, priapism, gynaecomastia, prostatic hyperplasia and accelerate growth of malignant prostate neoplasms.
Drug Interaction: Testosterone enanthate is known to interact with other drugs like ciclosporine, antidiabetics, thyroxine, anticoagulants. Always consult your physician for the change of dose regimen or an alternative drug of choice that may strictly be required.
Mechanism of Action: The effects of testosterone in humans and other vertebrates occur by way of two main mechanisms: by activation of the androgen receptor (directly or as DHT), and by conversion to estradiol and activation of certain estrogen receptors. Free testosterone (T) is transported into the cytoplasm of target tissue cells, where it can bind to the androgen receptor, or can be reduced to 5?-dihydrotestosterone (DHT) by the cytoplasmic enzyme 5?-reductase. DHT binds to the same androgen receptor even more strongly than T, so that its androgenic potency is about 2.5 times that of T. The T-receptor or DHT-receptor complex undergoes a structural change that allows it to move into the cell nucleus and bind directly to specific nucleotide sequences of the chromosomal DNA. The areas of binding are called hormone response elements (HREs), and influence transcriptional activity of certain genes, producing the androgen effects.
Pregnancy Impact: Studies in animals or humans have demonstrated fetal abnormalities and/or there is positive evidence of human fetal risk based on adverse reaction data from investigational or marketing experience, and the risks involved in use of the drug in pregnant women clearly outweigh potential benefits.
Impact During Lactation: Studies in breastfeeding mothers have demonstrated that there is significant and documented risk to the infant based on human experience, or it is a medication that has a high risk of causing significant damage to an infant. The risk of using the drug in breastfeeding women clearly outweighs any possible benefit from breastfeeding. The drug is contraindicated in women who are breastfeeding an infant.
Price of Cernos 40mg 10Capsule : Rs.122.33
Testosterone 40 mg
Use spaces to separate tags. Use single quotes (') for phrases.
BigChemist is truly professional company for 100% Original Medicines, Authentic vitamins, sport nutrition supplements and Beauty Products. We sell only the highest-grade substances needed for health and bodily growth. Engage with us for Bigger Life Experience!!
In compliance with Drug and Cosmetic Act and Rules, we don't process requests for Schedule X and other habit forming drugs. For Schedule H and H1 drugs a valid prescription from a registered medical practitioner needs to be uploaded with Order.