Comtrixo 200mg 10Tablet contains following Salts:-
Cefixime - Drug Information
Typical usage: :Infections of respiratory, urinary and biliary tract. Salmonella infection.
Probable Side Effects: :Pseudomembranous colitis, thrombocytopenia, thrombophlebitis, leucopenia, seizures, flatulence, dizziness, headache, nausea, vomiting, anorexia, diarrhea, abdominal pain, urticaria, pruritus, dyspepsia, hypersensitivity.
Drug Interaction: Probenecid may increase the blood concentration of cefixime by decreasing removal of cefixime by the kidney. May increase prothrombin time with anticoagulants.
Mechanism of Action: Cefixime binds to specific penicillin-binding proteins (PBPs) located inside the bacterial cell wall, causing the inhibition of the third and last stage of bacterial cell wall synthesis. Cell lysis is then mediated by bacterial cell wall autolytic enzymes such as autolysins; it is possible that cefixime interferes with an autolysin inhibitor.
Pregnancy Impact: Animal reproduction studies have failed to demonstrate a risk to the fetus and there are no adequate and well-controlled studies in pregnant women.
Impact During Lactation: There are no controlled studies in breastfeeding women, however the risk of untoward effects to a breastfed infant is possible; or, controlled studies show only minimal non-threatening adverse effects. Drugs should be given only if the potential benefit justifies the potential risk to the infant.
Codeine - Drug Information
Typical usage: :Mild to moderate pain; diarrhoea ; cough suppression
Probable Side Effects: :Dependence, withdrawal symptoms; nausea, vomiting, constipation; drowsiness, confusion; difficulty in micturition, ureteric or biliary spasms, urinary retention; dry mouth, dizziness, sweating, facial flushing, headache, vertigo, bradycardia, tachycardia, palpitations, orthostatic hypotension, hypothermia, restlessness, mood changes, decreased libido or potency, hallucination, miosis; raised intracranial pressure, muscle rigidity.
Drug Interaction: Enhanced depressant effects with alcohol, anaesthetics, anxiolytics, hypnotics, TCAs, antipsychotics. Possible CNS depression or excitation with MAOIs. May alter effects of other compounds e.g. cyclizine, mexiletine, cisapride, metoclopramide and domperidone.
Mechanism of Action: Codeine provides relief by blocking the ascending pain pathways by binding to opiate receptors found in the CNS. It also helps suppress cough by direct action in the medulla.
Pregnancy Impact: There is positive evidence of human fetal risk based on adverse reaction data from investigational or marketing experience or studies in humans, but potential benefits may warrant use of the drug in pregnant women despite potential risks.
Impact During Lactation: There is positive evidence of risk to a breastfed infant or to breastmilk production, but the benefits of use in breastfeeding mothers may be acceptable despite the risk to the infant (e.g. if the drug is needed in a life-threatening situation or for a serious disease for which safer drugs cannot be used or are ineffective).
Price of Comtrixo 200mg 10Tablet : Rs.79.00
|Dispatches by||Next Day|
|Composition||Cefixime 200 mg, Codeine 60 Million|
|Salt Information||Cefixime, Codeine|
|Brand Name||Comed Chemicals|
|Pack Size||10 Tablet|
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Substitutes of Comtrixo 200mg 10Tablet
Rs.1.00Cyper Drugs & Pharma
Rs.1.00Orchid Chemicals & Pharma
Rs.1.00Low Cost Standard Therapeutics (Locost)
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