Crocin Pain Relief contains following Salts:-
Caffeine - Drug Information
Typical usage: :Nsaids, Antirheumatoid Drugs
Probable Side Effects: :At doses > 600 mg per day, caffeine may cause anxiety, tachycardia (rapid heart rate), palpitations, insomnia, restlessness, nervousness, tremor and headache.
Drug Interaction: Phenytoin and smoking may decrease caffeine levels.Cimetidine, disulfiram, fluoroquinolones, mexiletine, oral contraceptives may increase the caffeine levels, enhancing the effects.
Mechanism of Action: Caffeine increases energy metabolism throughout the brain but decreases at the same time cerebral blood flow, inducing a relative brain hypoperfusion. Caffeine activates noradrenaline neurons and seems to affect the local release of dopamine which in turm produces the Central Nervous System Stimulant effect.
Pregnancy Impact: Animal reproduction studies have shown an adverse effect on the fetus and there are no adequate and well-controlled studies in humans, but potential benefits may warrant use of the drug in pregnant women despite potential risks.
Impact During Lactation: Studies in breastfeeding mothers have demonstrated that there is significant and documented risk to the infant based on human experience, or it is a medication that has a high risk of causing significant damage to an infant. The risk of using the drug in breastfeeding women clearly outweighs any possible benefit from breastfeeding. The drug is contraindicated in women who are breastfeeding an infant.
Paracetamol - Drug Information
Typical usage: :Ear pain, fever, headache, malaise, migraine, mild to moderate pain, pain, post-vaccine reaction, short-bowel syndrome.
Probable Side Effects: :Bronchospasm, blood dyscrasias, centribular necrosis, liver damage, hypoglycemic coma, hepatic necrosis, liver failure, skin rashes, GI adverse effects.
Drug Interaction: Paracetamol is known to interact with other drugs like alcohol, ascorbic acid, azilisartan medoxomil, busulphan, carbamazepine, chloramphenicol, cimetidine (HCl), diflunisal, interferon alpha, isoniazid, itopride (HCl), metoclopramide (HCl). Always consult your physician for the change of dose regimen or an alternative drug of choice that may strictly be required.
Mechanism of Action: Paracetamol is thought to act primarily in the CNS, increasing the pain threshold by inhibiting both isoforms of cyclooxygenase, COX-1, COX-2, and COX-3 enzymes involved in prostaglandin (PG) synthesis. Paracetamol indirectly blocks COX, and that this blockade is ineffective in the presence of peroxides. paracetamol is effective in the central nervous system and in endothelial cells but not in platelets and immune cells which have high levels of peroxides. The antipyretic properties of paracetamol are likely due to direct effects on the heat-regulating centres of the hypothalamus resulting in peripheral vasodilation, sweating and hence heat dissipation.
Pregnancy Impact: Animal reproduction studies have failed to demonstrate a risk to the fetus and there are no adequate and well-controlled studies in pregnant women.
Impact During Lactation: There are no controlled studies in breastfeeding women, however the risk of untoward effects to a breastfed infant is possible; or, controlled studies show only minimal non-threatening adverse effects. Drugs should be given only if the potential benefit justifies the potential risk to the infant.
Price of Crocin Pain Relief : Rs.25.00
|Dispatches by||Next Day|
|Composition||Caffeine 50 mg, Paracetamol 650 mg|
|Salt Information||Caffeine, Paracetamol|
|Pack Size||10 Tablet|
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Substitutes of Crocin Pain Relief
Rs.1.00Cyper Drugs & Pharma
Rs.1.00Orchid Chemicals & Pharma
Rs.1.00Low Cost Standard Therapeutics (Locost)
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