Dolobak 450Mg/100Mg 10Tablet contains following Salts:-
Chlormezanone - Drug Information
Indications Chlormezanone Binds To Central Benzodiazepine Receptors Which Interact Allosterically With GABA Receptors. This Potentiates The Effects Of The Inhibitory Neurotransmitter GABA, Increasing The Inhibition Of The Ascending Reticular Activating System And Blocking The Cortical And Limbic Arousal That Occurs Following Stimulation Of The Reticular Pathways.
Dosage Chlormezanone 100 Mg Oral Tablet
Contra-Indications Pregnancy and lactation.
Side Effects Drowsiness, Weakness, Nausea, Dizziness, Skin Rash, Flushing Of Skin, Confusion, Excitement, Depression , Dryness Of Mouth, Cholestatic Jaundice May Occur, Erthyema Mutliforme, Stevens- Johnson Syndrome, Toxic Epidermal Necrolysis.
Special Precautions Impaired renal/liver function. Pregnancy & lactation
Drug-Interaction Tell Your Doctor Of All Prescription And Nonprescription Medication You May Use. Do Not Start Or Stop Any Medicine Without Doctor Or Pharmacist Approval
Paracetamol - Drug Information
Typical usage: :Ear pain, fever, headache, malaise, migraine, mild to moderate pain, pain, post-vaccine reaction, short-bowel syndrome.
Probable Side Effects: :Bronchospasm, blood dyscrasias, centribular necrosis, liver damage, hypoglycemic coma, hepatic necrosis, liver failure, skin rashes, GI adverse effects.
Drug Interaction: Paracetamol is known to interact with other drugs like alcohol, ascorbic acid, azilisartan medoxomil, busulphan, carbamazepine, chloramphenicol, cimetidine (HCl), diflunisal, interferon alpha, isoniazid, itopride (HCl), metoclopramide (HCl). Always consult your physician for the change of dose regimen or an alternative drug of choice that may strictly be required.
Mechanism of Action: Paracetamol is thought to act primarily in the CNS, increasing the pain threshold by inhibiting both isoforms of cyclooxygenase, COX-1, COX-2, and COX-3 enzymes involved in prostaglandin (PG) synthesis. Paracetamol indirectly blocks COX, and that this blockade is ineffective in the presence of peroxides. paracetamol is effective in the central nervous system and in endothelial cells but not in platelets and immune cells which have high levels of peroxides. The antipyretic properties of paracetamol are likely due to direct effects on the heat-regulating centres of the hypothalamus resulting in peripheral vasodilation, sweating and hence heat dissipation.
Pregnancy Impact: Animal reproduction studies have failed to demonstrate a risk to the fetus and there are no adequate and well-controlled studies in pregnant women.
Impact During Lactation: There are no controlled studies in breastfeeding women, however the risk of untoward effects to a breastfed infant is possible; or, controlled studies show only minimal non-threatening adverse effects. Drugs should be given only if the potential benefit justifies the potential risk to the infant.
Price of Dolobak 450Mg/100Mg 10Tablet : Rs.52.00
|Dispatches by||Next Day|
|Composition||Chlormezanone 100 mg, Paracetamol 450 mg|
|Salt Information||Chlormezanone, Paracetamol|
|Brand Name||Micro Labs|
|Pack Size||10 Tablet|
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Substitutes of Dolobak 450Mg/100Mg 10Tablet
Rs.1.00Cyper Drugs & Pharma
Rs.1.00Orchid Chemicals & Pharma
Rs.1.00Low Cost Standard Therapeutics (Locost)
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