Dynapar Ld 25Mg/325Mg 10Capsule contains following Salts:-
Diclofenac - Drug Information
Typical usage: :Adnexitis, dysmenorrhoea, inflammation, migraine, post-operative pain, post-traumatic pain, rheumatoid arthritis.
Probable Side Effects: :Dizziness, vertigo, headache, rashes, GI upset, elevation of liver enzymes, GI hemorrhage, vision disturbances, erythema multiforme.
Drug Interaction: Diclofenac is known to interact with other drugs like cholestyramine, colestipol (HCl), cyclosporin A, misoprostol, nitrendipine, sucralfate. Always consult your physician for the change of dose regimen or an alternative drug of choice that may strictly be required.
Mechanism of Action: Diclofenac inhibits both leukocyte migration and the enzyme cylooxygenase (COX-1 and COX-2), leading to the peripheral inhibition of prostaglandin synthesis. As prostaglandins sensitize pain receptors, inhibition of their synthesis is responsible for the analgesic effects of diclofenac. Antipyretic effects may be due to action on the hypothalamus, resulting in peripheral dilation, increased cutaneous blood flow, and subsequent heat dissipation.
Pregnancy Impact: Animal reproduction studies have shown an adverse effect on the fetus and there are no adequate and well-controlled studies in humans, but potential benefits may warrant use of the drug in pregnant women despite potential risks.
Impact During Lactation: There is positive evidence of risk to a breastfed infant or to breastmilk production, but the benefits of use in breastfeeding mothers may be acceptable despite the risk to the infant (e.g. if the drug is needed in a life-threatening situation or for a serious disease for which safer drugs cannot be used or are ineffective).
Paracetamol - Drug Information
Typical usage: :Ear pain, fever, headache, malaise, migraine, mild to moderate pain, pain, post-vaccine reaction, short-bowel syndrome.
Probable Side Effects: :Bronchospasm, blood dyscrasias, centribular necrosis, liver damage, hypoglycemic coma, hepatic necrosis, liver failure, skin rashes, GI adverse effects.
Drug Interaction: Paracetamol is known to interact with other drugs like alcohol, ascorbic acid, azilisartan medoxomil, busulphan, carbamazepine, chloramphenicol, cimetidine (HCl), diflunisal, interferon alpha, isoniazid, itopride (HCl), metoclopramide (HCl). Always consult your physician for the change of dose regimen or an alternative drug of choice that may strictly be required.
Mechanism of Action: Paracetamol is thought to act primarily in the CNS, increasing the pain threshold by inhibiting both isoforms of cyclooxygenase, COX-1, COX-2, and COX-3 enzymes involved in prostaglandin (PG) synthesis. Paracetamol indirectly blocks COX, and that this blockade is ineffective in the presence of peroxides. paracetamol is effective in the central nervous system and in endothelial cells but not in platelets and immune cells which have high levels of peroxides. The antipyretic properties of paracetamol are likely due to direct effects on the heat-regulating centres of the hypothalamus resulting in peripheral vasodilation, sweating and hence heat dissipation.
Pregnancy Impact: Animal reproduction studies have failed to demonstrate a risk to the fetus and there are no adequate and well-controlled studies in pregnant women.
Impact During Lactation: There are no controlled studies in breastfeeding women, however the risk of untoward effects to a breastfed infant is possible; or, controlled studies show only minimal non-threatening adverse effects. Drugs should be given only if the potential benefit justifies the potential risk to the infant.
Price of Dynapar Ld 25Mg/325Mg 10Capsule : Rs.24.00
|Dispatches by||Next Day|
|Composition||Diclofenac 25 mg, Paracetamol 325 mg|
|Salt Information||Diclofenac, Paracetamol|
|Brand Name||Troikaa Pharma|
|Pack Size||10 Capsule|
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Substitutes of Dynapar Ld 25Mg/325Mg 10Capsule
Rs.1.00Cyper Drugs & Pharma
Rs.1.00Orchid Chemicals & Pharma
Rs.1.00Low Cost Standard Therapeutics (Locost)
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