Dyrade M contains following Salts:-
Diloxanide Furoate - Drug Information
Typical usage: :Asymptomatic cyst passers, mild amebic dysentery, non-dysenteric intestinal amebiasis, oliguria due to renal failure, parkinsonism.
Probable Side Effects: :Flatulence, nausea, vomiting, anorexia, diarrhea, abdominal cramps, urticaria, esophagitis, paresthesias, albuminuria.
Drug Interaction: Tell your doctor of all prescription and nonprescription medication you may use. Do not start or stop any medicine without doctor or pharmacist approval.
Mechanism of Action: Diloxanide furoate destroys the trophozoites of E. histolytica that eventually form into cysts. The cysts are then excreted by persons infected with asymptomatic amebiasis.
Pregnancy Impact: No Studies Available
Impact During Lactation: No Studies Available
Metronidazole - Drug Information
Typical usage: :Amoebiasis, giardiasis, trichomonas vaginitis, anaerobic infections, ulcerative gingivitis. Eradication of H.pylori associated with peptic ulcer disease. Antibiotic-associated coulitis. Trichomoniasis, Balantidiasis, Blastocyatis hominis infection. Adjunct to treatment of chronic periodontal infections. Rosacea.
Probable Side Effects: :GI disturbances e.g. nausea, unpleasant metallic taste, vomiting, diarrhoea or constipation. Furred tongue, glossitis, and stomatitis due to overgrowth of Candida. Rarely, antibiotic-associated colitis. Weakness, dizziness, ataxia, headache, drowsiness, insomnia, changes in mood or mental state. Numbness or tingling in the extremities, epileptiform seizures (high doses or prolonged treatment). Transient leucopenia and thrombocytopenia. Hypersensitivity reactions. Anaphylaxis.
Drug Interaction: Acute psychoses or confusion with disulfiram. It has synergistic effect with other antimicrobials. Effects reduced with phenobarbital or phenytoin. Disulfiram-like reaction with alcohol. Increased risk of adverse effects of coumarin anticoagulants, phenytoin, lithium, ciclosporin, fluorouracil. Increased risk of neurological effects with cimetidine.
Mechanism of Action: Metronidazole is converted to reduction products that interact with DNA to cause destruction of helical DNA structure and strand leading to a protein synthesis inhibition and cell death in susceptible organisms. It is effective against a wide range of organisms including E. histolytica, T. vaginalis, Giardia, anaerobes e.g. Bacterioides sp, Fusobacterium sp, Clostridium sp.
Pregnancy Impact: Animal reproduction studies have failed to demonstrate a risk to the fetus and there are no adequate and well-controlled studies in pregnant women.
Impact During Lactation: Drug which has been studied in a limited number of breastfeeding women without an increase in adverse effects in the infant; And/or, the evidence of a demonstrated risk which is likely to follow use of this medication in a breastfeeding woman is remote.
Price of Dyrade M : Rs.7.00
|Dispatches by||Next Day|
|Composition||Diloxanide 250 mg, Metronidazole 200 mg|
|Salt Information||Diloxanide, Metronidazole|
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Substitutes of Dyrade M
Rs.1.00Cyper Drugs & Pharma
Rs.1.00Orchid Chemicals & Pharma
Rs.1.00Low Cost Standard Therapeutics (Locost)
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