Dytor Plus 10 contains following Salts:-
Spironolactone - Drug Information
Typical usage: :All forms of epilepsy, Congestive heart failure, Electrolyte disorder, For prophylaxis in pregnancy, Hirsutism, Hyperaldoesteronism, Hypertension, Myoclonus, Nephrotic syndrome, Oedema, Oedema and ascites in cirrhosis of the liver, Parkinson's disease; drug-induced extrapyramidal symptoms, Primary hyperaldosteronism, Tobacco amblyopia and leber's optic atrophy.
Probable Side Effects: :Diarrhea, Drowsiness, Dizziness, Mental confusion.
Drug Interaction: Sodium excretion effect may be inhibited by aspirin. May reduce ulcer-healing properties of carbenoxolone.
Mechanism of Action: Spironolactone acts on the distal renal tubules as a competitive antagonist of aldosterone. It increases the excretion of sodium chloride and water while conserving potassium and hydrogen ions.
Pregnancy Impact: Animal reproduction studies have shown an adverse effect on the fetus and there are no adequate and well-controlled studies in humans, but potential benefits may warrant use of the drug in pregnant women despite potential risks.
Impact During Lactation: Studies in breastfeeding mothers have demonstrated that there is significant and documented risk to the infant based on human experience, or it is a medication that has a high risk of causing significant damage to an infant. The risk of using the drug in breastfeeding women clearly outweighs any possible benefit from breastfeeding. The drug is contraindicated in women who are breastfeeding an infant.
Torasemide - Drug Information
Typical usage: :Congestive heart failure, edema, hepatic disease, hypertension, renal diseases.
Probable Side Effects: :Hypotension, dehydration, hemoconcentration, hypokalemia, hypochloremic alkalosis, hypovolemia, hyponatremia.
Drug Interaction: Torasemide is known to interact with other drugs like amifostine, capecitabine, cholestyramine, colestipol (HCl), floxuridine, luconazole, fluorouracil, flurbiprofen, gemfibrozil, ibuprofen, indomethacin, ketoconazole, mefenamic acid, miconazole (Nitrate), niaprazine, perindopril, pirbuterol (Acetate), piroxicam, rituximab, sulfisoxazole, sulphadiazine, tolbutamide. Always consult your physician for the change of dose regimen or an alternative drug of choice that may strictly be required.
Mechanism of Action: Torasemide inhibits the Na+/K+/2Cl--carrier system (via interference of the chloride binding site) in the lumen of the thick ascending portion of the loop of Henle, resulting in a decrease in reabsorption of sodium and chloride. This results in an increase in the rate of delivery of tubular fluid and electrolytes to the distal sites of hydrogen and potassium ion secretion, while plasma volume contraction increases aldosterone production. The increased delivery and high aldosterone levels promote sodium reabsorption at the distal tubules, and By increasing the delivery of sodium to the distal renal tubule, torasemide indirectly increases potassium excretion via the sodium-potassium exchange mechanism. Thus torasemide increases the urinary excretion of sodium, chloride, and water, but it does not significantly alter glomerular filtration rate, renal plasma flow, or acid-base balance.
Pregnancy Impact: Animal reproduction studies have failed to demonstrate a risk to the fetus and there are no adequate and well-controlled studies in pregnant women.
Impact During Lactation: There are no controlled studies in breastfeeding women, however the risk of untoward effects to a breastfed infant is possible; or, controlled studies show only minimal non-threatening adverse effects. Drugs should be given only if the potential benefit justifies the potential risk to the infant.
Price of Dytor Plus 10 : Rs.50.50
|Dispatches by||Next Day|
|Composition||Spironolactone 50 mg, Torasemide 10 mg|
|Salt Information||Spironolactone, Torasemide|
|Pack Size||15 Tablet|
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Substitutes of Dytor Plus 10
Rs.1.00Cyper Drugs & Pharma
Rs.1.00Orchid Chemicals & Pharma
Rs.1.00Low Cost Standard Therapeutics (Locost)
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