Typical usage: :Hypercholesterolaemia, hyperlipoproteinaemia, prophylaxis of NSAID-associated gastric or duodenal ulcer.
Probable Side Effects: :Hepatitis, rhabdomyolysis, headache, diarrhea, myalgia, constipation, skin rashes, impotence, decrease in libido.
Drug Interaction: Fenofibrate is known to interact with other drugs like Acenocoumarol, Anisindione, Cerivastatin, Dicumarol, Lovastatin, Pravastatin. Always consult your physician for the change of dose regimen or an alternative drug of choice that may strictly be required.
Mechanism of Action: Fenofibrate exerts its therapeutic effects through activation of peroxisome proliferator activated receptor a (PPARa). This increases lipolysis and elimination of triglyceride-rich particles from plasma by activating lipoprotein lipase and reducing production of apoprotein C-III.
Pregnancy Impact: Animal reproduction studies have shown an adverse effect on the fetus and there are no adequate and well-controlled studies in humans, but potential benefits may warrant use of the drug in pregnant women despite potential risks.
Impact During Lactation: There are no controlled studies in breastfeeding women, however the risk of untoward effects to a breastfed infant is possible; or, controlled studies show only minimal non-threatening adverse effects. Drugs should be given only if the potential benefit justifies the potential risk to the infant.
Price of Fenolip 145Mg : Rs.121.00
Fenofibrate 145 mg
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