Typical usage: :Folate-deficient. Megaloblastic anaemia. Prophylaxis of megaloblastic anemia in pregnancy. Prophylaxis of neural tube defect in pregnancy. Malabsorption syndromes. Antiepileptic therapy.
Probable Side Effects: :Neuropathy, bronchospasm, itchy skin eruptions, malaise.
Drug Interaction: Interacts with other drugs like deferoxamine, epoetin, fosphenytoin, methotrexate, sulphasalazine. These interactions are sometimes beneficial and sometimes may pose threats to life. Always consult your physician for the change of dose regimen or an alternative drug of choice that may strictly be required.
Mechanism of Action: Folic acid, as it is biochemically inactive, is converted to tetrahydrofolic acid and methyltetrahydrofolate by dihydrofolate reductase. These folic acid congeners are transported across cells by receptor-mediated endocytosis where they are needed to maintain normal erythropoiesis, synthesize purine and thymidylate nucleic acids, interconvert amino acids, methylate tRNA, and generate and use formate. Using vitamin B12 as a cofactor, folic acid can normalize high homocysteine levels by remethylation of homocysteine to methionine via methionine synthetase.
Pregnancy Impact: Adequate and well-controlled studies have failed to demonstrate a risk to the fetus in the first trimester of pregnancy (and there is no evidence of risk in later trimesters).
Impact During Lactation: Drug which has been taken by a large number of breastfeeding mothers without any observed increase in adverse effects in the infant. Controlled studies in breastfeeding women fail to demonstrate a risk to the infant and the possibility of harm to the breastfeeding infant is remote; or the product is not orally bioavailable in an infant.
Probable Side Effects: :Stomach upset and pain, constipation or diarrhea, nausea, and vomiting.
Drug Interaction: Iron is known to interact with other drugs like ciprofloxacin, clodronate, deferiprone, demeclocycline, etidronic acid, gemifloxacin, ibandronate, levofloxacin, methyldopa, moxifloxacin, norfloxacin. Always consult your physician for the change of dose regimen or an alternative drug of choice that may strictly be required.
Mechanism of Action: Iron is necessary for the production of hemoglobin. Iron-deficiency can lead to decreased production of hemoglobin and a microcytic, hypochromic anemia.
Pregnancy Impact: No Studies Available
Impact During Lactation: No Studies Available
Price of Ferium D3 Chewable Tablet : Rs.108.80
Folic Acid 350 mcg, Iron 100 mg
Folic Acid, Iron
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