Fossical 35mg 4Tablet contains following Salts:-
Risedronate - Drug Information
Typical usage: :Pagets disease of bone. Treatment and prophylaxis of postmenopausal or corticosteroid-induced osteoporosis.
Probable Side Effects: :Diarrhea, Constipation, Abdominal pain, Nausea and vomiting.
Drug Interaction: Pagets disease of bone. Treatment and prophylaxis of postmenopausal or corticosteroid-induced osteoporosis.
Mechanism of Action: The action of risedronate on bone tissue is based partly on its affinity for hydroxyapatite, which is part of the mineral matrix of bone. Risedronate also targets farnesyl pyrophosphate (FPP) synthase. Nitrogen-containing bisphosphonates (such as pamidronate, alendronate, risedronate, ibandronate and zoledronate) appear to act as analogues of isoprenoid diphosphate lipids, thereby inhibiting FPP synthase, an enzyme in the mevalonate pathway. Inhibition of this enzyme in osteoclasts prevents the biosynthesis of isoprenoid lipids (FPP and GGPP) that are essential for the post-translational farnesylation and geranylgeranylation of small GTPase signalling proteins. This activity inhibits osteoclast activity and reduces bone resorption and turnover. In postmenopausal women, it reduces the elevated rate of bone turnover, leading to, on average, a net gain in bone mass.
Pregnancy Impact: Animal reproduction studies have shown an adverse effect on the fetus and there are no adequate and well-controlled studies in humans, but potential benefits may warrant use of the drug in pregnant women despite potential risks.
Impact During Lactation: There are no controlled studies in breastfeeding women, however the risk of untoward effects to a breastfed infant is possible; or, controlled studies show only minimal non-threatening adverse effects. Drugs should be given only if the potential benefit justifies the potential risk to the infant.
Price of Fossical 35mg 4Tablet : Rs.98.00
|Dispatches by||Next Day|
|Composition||Risedronate 35 mg|
|Pack Size||4 Tablet|
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Substitutes of Fossical 35mg 4Tablet
Rs.1.00Cyper Drugs & Pharma
Rs.1.00Orchid Chemicals & Pharma
Rs.1.00Low Cost Standard Therapeutics (Locost)
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