Gnaton Total 10Capsule contains following Salts:-
Itopride - Drug Information
Typical usage: :Non-ulcer dyspepsia (chronic gastritis) ie, sensation of bloating, early satiety, upper abdominal pain or discomfort, anorexia, heartburn, nausea and vomiting.
Probable Side Effects: :Leukopenia, thrombocytopenia, anaphylactoid reaction, increased prolactin level and gynecomastia, dizziness, headache and tremor, diarrhea, constipation, abdominal pain, increased saliva and nausea, Jaundice, rash, redness and itching.
Drug Interaction: Itopride is known to interact with other drugs like warfarin, diazepam, diclofenac sodium, ticlopidine HCl, nifedipine, nicardipine HCl. Always consult your physician for the change of dose regimen or an alternative drug of choice that may strictly be required.
Mechanism of Action: Itopride has anticholinesterase (AchE) activity as well as dopamine D2 receptor antagonistic activity through dopamine D2 receptor antagonism, removes the inhibitory effects on acetylcholine (Ach) release. It also inhibits the enzyme AchE which prevents the degradation of ACh. The net effect is an increase in ACh concentration, which in turn, promotes gastric motility, increases the lower esophageal sphincter pressure, accelerates gastric emptying and improves gastro-duodenal coordination.
Pregnancy Impact: No Studies Available
Impact During Lactation: No Studies Available
Pantoprazole - Drug Information
Typical usage: :Duodenal ulcer. Gastric ulcer. Reflux oesophagitis. Prophylaxis of NSAID associated peptic ulcer. Zollinger-ellison syndrome and other hypersecretory states.
Probable Side Effects: :Weakness, dizziness, nausea, vomiting, anxiety, dyspnea, pain, pharyngitis, cough, arthralgia, rhinitis, chest pain, bronchitis, backache, urinary frequency, UTI, hyperlipidemia.
Drug Interaction: Pantoprazole is known to interact with other drugs like ampicillin, atazanavir, clarithromycin, clopidogrel, digoxin, ketoconazole, warfarin (Na).
Mechanism of Action: Pantoprazole is a proton pump inhibitor (PPI) that suppresses the final step in gastric acid production by forming a covalent bond to two sites of the (H+,K+ )- ATPase enzyme system at the secretory surface of the gastric parietal cell. This effect is dose- related and leads to inhibition of both basal and stimulated gastric acid secretion irrespective of the stimulus.
Pregnancy Impact: Animal reproduction studies have failed to demonstrate a risk to the fetus and there are no adequate and well-controlled studies in pregnant women.
Impact During Lactation: Studies in breastfeeding mothers have demonstrated that there is significant and documented risk to the infant based on human experience, or it is a medication that has a high risk of causing significant damage to an infant. The risk of using the drug in breastfeeding women clearly outweighs any possible benefit from breastfeeding. The drug is contraindicated in women who are breastfeeding an infant.
Price of Gnaton Total 10Capsule : Rs.163.00
|Dispatches by||Next Day|
|Composition||Itopride 150 mg, Pantoprazole 40 mg|
|Salt Information||Itopride, Pantoprazole|
|Pack Size||10 Capsule|
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Substitutes of Gnaton Total 10Capsule
Rs.1.00Cyper Drugs & Pharma
Rs.1.00Orchid Chemicals & Pharma
Rs.1.00Low Cost Standard Therapeutics (Locost)
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