Histakof Syrup 60Ml contains following Salts:-
Chlorphenamine - Drug Information
Typical usage: :Allergic conditions. Adjunct in the emergency treatment of anaphylactic shock.
Probable Side Effects: :CNS depression, sedation, drowsiness, lassitude, dizziness. GI upsets, anorexia, or increased appetite, epigastric pain, blurring of vision, dysuria, dryness of mouth, tightness in chest, hypotension, muscular weakness, tinnitus, euphoria, headache, paradoxical CNS stimulation. CV collapse and respiratory failure.
Drug Interaction: Potentiates sedative effect of psychotropic drugs e.g. barbiturates, hypnotics, opioid analgesics, anxiolytics and antipsychotics. Interaction with alcohol could be dangerous (sedation/excitation).
Mechanism of Action: Chlorphenamine is an H1-receptor antagonist which competetively blocks H1-receptor sites on tissues.
Pregnancy Impact: Animal reproduction studies have failed to demonstrate a risk to the fetus and there are no adequate and well-controlled studies in pregnant women.
Impact During Lactation: Drug which has been studied in a limited number of breastfeeding women without an increase in adverse effects in the infant; And/or, the evidence of a demonstrated risk which is likely to follow use of this medication in a breastfeeding woman is remote.
Dextromethorphan - Drug Information
Typical usage: :Dry cough.
Probable Side Effects: :Dependency, dizziness, drowsiness, vomiting, restlessness, mental confusion, excitation.
Drug Interaction: Dextromethorphan is known to interact with other drugs like abiraterone acetate, amiodarone (HCl), fluoxetine (HCl), haloperidol, mitomycin C, moclobemide, paroxetine, phenelzine, propafenone (HCl), quinidine, sibutramine. Always consult your physician for the change of dose regimen or an alternative drug of choice that may strictly be required.
Mechanism of Action: Dextromethorphan is an opioid-like drug that binds to and acts as antagonist to the NMDA glutamatergic receptor, it is an agonist to the opioid sigma 1 and sigma 2 receptors, it is also an alpha3/beta4 nicotinic receptor antagonist and targets the serotonin reuptake pump. Dextromethorphan is rapidly absorbed from the gastrointestinal tract, where it enters the bloodstream and crosses the blood-brain barrier.
Pregnancy Impact: Animal reproduction studies have shown an adverse effect on the fetus and there are no adequate and well-controlled studies in humans, but potential benefits may warrant use of the drug in pregnant women despite potential risks.
Impact During Lactation: There are no controlled studies in breastfeeding women, however the risk of untoward effects to a breastfed infant is possible; or, controlled studies show only minimal non-threatening adverse effects. Drugs should be given only if the potential benefit justifies the potential risk to the infant.
Menthol - Drug Information
Typical usage: :Pharmaceutical Aid
Probable Side Effects: :Nystagmus, contact dermatitis, apnea. Menthol produces potentially life-threatening effects which include Coma. Overdosage of Menthol include Irregularities in heart rhythm. The symtomatic adverse effects produced by menthol such as vertigo, drowsiness, ataxia, abdominal pain, nausea and vomiting.
Drug Interaction: Menthol is known to interact with other drugs like Alcohol. These interactions are sometimes beneficial and sometimes may pose threats to life. Always consult your physician for the change of dose regimen or an alternative drug of choice that may strictly be required.
Mechanism of Action: Menthol primarily activates the cold-sensitive TRPM8 receptors in the skin. Menthol, after topical application, causes a feeling of coolness due to stimulation of 'cold' receptors by inhibiting Ca++ currents of neuronal membranes. It may also yield analgesic properties via kappa-opioid receptor agonism.
Pregnancy Impact: There is positive evidence of human fetal risk based on adverse reaction data from investigational or marketing experience or studies in humans, but potential benefits may warrant use of the drug in pregnant women despite potential risks.
Impact During Lactation: There is positive evidence of risk to a breastfed infant or to breastmilk production, but the benefits of use in breastfeeding mothers may be acceptable despite the risk to the infant (e.g. if the drug is needed in a life-threatening situation or for a serious disease for which safer drugs cannot be used or are ineffective).
Price of Histakof Syrup 60Ml : Rs.26.00
|Dispatches by||Next Day|
|Composition||Chlorphenamine 2 mg, Dextromethorphan 5 mg, Menthol, Pseudoephedrine Hydrochloride 15 mg|
|Salt Information||Chlorphenamine, Dextromethorphan, Menthol, Pseudoephedrine Hydrochloride|
|Brand Name||Kopran Pharma|
|Pack Size||60 ml|
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Substitutes of Histakof Syrup 60Ml
Rs.1.00Cyper Drugs & Pharma
Rs.1.00Orchid Chemicals & Pharma
Rs.1.00Low Cost Standard Therapeutics (Locost)
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