Idrofos contains following Salts:-
Ibandronic Acid - Drug Information
Typical usage: :Hypercalcaemia due to malignancy, hypercalcaemia of malignancy.
Probable Side Effects: :Fever, chills, bone pain, influenza like syndrome, hypersensitivity reactions, bronchospasm, angioedema, muscle pain.
Drug Interaction: Hypercalcaemia due to malignancy, hypercalcaemia of malignancy.
Mechanism of Action: The action of ibandronate on bone tissue is based partly on its affinity for hydroxyapatite, which is part of the mineral matrix of bone. Nitrogen-containing bisphosphonates (such as pamidronate, alendronate, risedronate, ibandronate and zoledronate) appear to act as analogues of isoprenoid diphosphate lipids, thereby inhibiting farnesyl pyrophosphate (FPP) synthase, an enzyme in the mevalonate pathway. Inhibition of this enzyme in osteoclasts prevents the biosynthesis of isoprenoid lipids (FPP and GGPP) that are essential for the post-translational farnesylation and geranylgeranylation of small GTPase signalling proteins. This activity inhibits osteoclast activity and reduces bone resorption and turnover.
Pregnancy Impact: Animal reproduction studies have shown an adverse effect on the fetus and there are no adequate and well-controlled studies in humans, but potential benefits may warrant use of the drug in pregnant women despite potential risks.
Impact During Lactation: There are no controlled studies in breastfeeding women, however the risk of untoward effects to a breastfed infant is possible; or, controlled studies show only minimal non-threatening adverse effects. Drugs should be given only if the potential benefit justifies the potential risk to the infant.
Price of Idrofos : Rs.3,055.00
|Dispatches by||Next Day|
|Composition||Ibandronic Acid 1 mg|
|Salt Information||Ibandronic Acid|
|Brand Name||Sun Pharma|
|Pack Size||6 ml in Vial|
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Substitutes of Idrofos
Rs.1.00Cyper Drugs & Pharma
Rs.1.00Orchid Chemicals & Pharma
Rs.1.00Low Cost Standard Therapeutics (Locost)
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