Insugen N 40Iu Injection contains following Salts:-
Insulin Isophane - Drug Information
Typical usage: :Diabetes mellitus.
Probable Side Effects: :Injection site reactions e.g. swelling, redness, itch and pain.
Drug Interaction: Insulin isophane is known to interact with other drugs like MAOIs, ACE inhibitors, salicylates, alcohol, anabolic steroids and non-selective ÃŽÂ²-blockers. Always consult your physician for the change of dose regimen or an alternative drug of choice that may strictly be required.
Mechanism of Action: Insulin isophane binds to the insulin receptor (IR), a heterotetrameric protein consisting of two extracellular alpha units and two transmembrane beta units. The binding of insulin to the alpha subunit of IR stimulates the tyrosine kinase activity intrinsic to the beta subunit of the receptor. The bound receptor is able to autophosphorylate and phosphorylate numerous intracellular substrates such as insulin receptor substrates (IRS) proteins, Cbl, APS, Shc and Gab 1. These activated proteins, in turn, lead to the activation of downstream signaling molecules including PI3 kinase and Akt. Akt regulates the activity of glucose transporter 4 (GLUT4) and protein kinase C (PKC) which play a critical role in metabolism and catabolism.
Pregnancy Impact: No Studies Available
Impact During Lactation: No Studies Available
Price of Insugen N 40Iu Injection : Rs.150.87
|Dispatches by||Next Day|
|Composition||Insulin Isophane NPH 40 iu|
|Salt Information||Insulin Isophane|
|Pack Size||1 Unit in Vial|
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Substitutes of Insugen N 40Iu Injection
Rs.1.00Cyper Drugs & Pharma
Rs.1.00Orchid Chemicals & Pharma
Rs.1.00Low Cost Standard Therapeutics (Locost)
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