Megatil (50 Mg) contains following Salts:-
Chlorpromazine - Drug Information
Typical usage: :Agitated states in the elderly, agitation, agitation and restlessness in the elderly, autism, childhood schizophrenia, conduct disorder with hyperactivity, control of agitated states in elderly without confusion, enhance permeation of SC or IM inj, hiccup due to gastric distension in palliative care, induction of labour, intractable hiccup, locally advanced or metastatic pancreatic cancer, mania, muscle spasm of varied aeitology, NSAID-associated gastric and duodenal ulcers.
Probable Side Effects: :Seizures, blood dyscrasias, neuroleptic malignant syndrome, temperature disorders, ventricular arrhythmias, jaundice, tachycardia, hypothermia, tachypnea, dizziness, headache, drowsiness, constipation, insomnia, skin rashes, dry mouth, blurred vision, allergic reactions, akathisia, weight gain, diaphoresis, acute dystonia, skin pigmentation, decrease in libido.
Drug Interaction: Chlorpromazine is known to interact with other drugs like alcohol, belladona, benzhexol (HCl), benztropine (Mesylate), bethanidine (Sulphate), bovine Insulin, cimetidine (HCl), clonidine (HCl), cyclophosphamide, debrisoquine (Sulphate), dexamphetamine (Sulphate), diazoxide, disulfiram, epirubicin, fosphenytoin, glibornuride, gliquidone, guanethidine, human insulin, imipramine (HCl), insulin lispro, lithium, metacycline (HCl). Always consult your physician for the change of dose regimen or an alternative drug of choice that may strictly be required.
Mechanism of Action: Chlorpromazine acts as an antagonist (blocking agent) on different postsysnaptic receptors -on dopaminergic-receptors (subtypes D1, D2, D3 and D4 - different antipsychotic properties on productive and unproductive symptoms), on serotonergic-receptors (5-HT1 and 5-HT2, with anxiolytic, antidepressive and antiaggressive properties as well as an attenuation of extrapypramidal side-effects, but also leading to weight gain, fall in blood pressure, sedation and ejaculation difficulties), on histaminergic-receptors (H1-receptors, sedation, antiemesis, vertigo, fall in blood pressure and weight gain), alpha1/alpha2-receptors (antisympathomimetic properties, lowering of blood pressure, reflex tachycardia, vertigo, sedation, hypersalivation and incontinence as well as sexual dysfunction, but may also attenuate pseudoparkinsonism - controversial) and finally on muscarinic (cholinergic) M1/M2-receptors (causing anticholinergic symptoms like dry mouth, blurred vision, obstipation, difficulty/inability to urinate, sinus tachycardia, ECG-changes and loss of memory, but the anticholinergic action may attenuate extrapyramidal side-effects).
Pregnancy Impact: Animal reproduction studies have shown an adverse effect on the fetus and there are no adequate and well-controlled studies in humans, but potential benefits may warrant use of the drug in pregnant women despite potential risks.
Impact During Lactation: Studies in breastfeeding mothers have demonstrated that there is significant and documented risk to the infant based on human experience, or it is a medication that has a high risk of causing significant damage to an infant. The risk of using the drug in breastfeeding women clearly outweighs any possible benefit from breastfeeding. The drug is contraindicated in women who are breastfeeding an infant.
Price of Megatil (50 Mg) : Rs.8.00
|Dispatches by||Next Day|
|Composition||Chlorpromazine 50 mg|
|Brand Name||Intas Laboratories|
|Pack Size||10 Tablet|
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Substitutes of Megatil (50 Mg)
Rs.1.00Cyper Drugs & Pharma
Rs.1.00Orchid Chemicals & Pharma
Rs.1.00Low Cost Standard Therapeutics (Locost)
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