Probable Side Effects: :Dizziness, vertigo, headache, rashes, GI upset, elevation of liver enzymes, GI hemorrhage, vision disturbances, erythema multiforme.
Drug Interaction: Diclofenac is known to interact with other drugs like cholestyramine, colestipol (HCl), cyclosporin A, misoprostol, nitrendipine, sucralfate. Always consult your physician for the change of dose regimen or an alternative drug of choice that may strictly be required.
Mechanism of Action: Diclofenac inhibits both leukocyte migration and the enzyme cylooxygenase (COX-1 and COX-2), leading to the peripheral inhibition of prostaglandin synthesis. As prostaglandins sensitize pain receptors, inhibition of their synthesis is responsible for the analgesic effects of diclofenac. Antipyretic effects may be due to action on the hypothalamus, resulting in peripheral dilation, increased cutaneous blood flow, and subsequent heat dissipation.
Pregnancy Impact: Animal reproduction studies have shown an adverse effect on the fetus and there are no adequate and well-controlled studies in humans, but potential benefits may warrant use of the drug in pregnant women despite potential risks.
Impact During Lactation: There is positive evidence of risk to a breastfed infant or to breastmilk production, but the benefits of use in breastfeeding mothers may be acceptable despite the risk to the infant (e.g. if the drug is needed in a life-threatening situation or for a serious disease for which safer drugs cannot be used or are ineffective).
Probable Side Effects: :Seizures, jaundice, leucopenia, hemolytic anemia, dizziness, headache, drowsiness, irritability, nervousness, nausea and vomiting, gastrointestinal disturbances.
Drug Interaction: Metaxalone is known to interact with other drugs like oxymorphone. Always consult your physician for the change of dose regimen or an alternative drug of choice that may strictly be required.
Mechanism of Action: Metaxalone shows muscle relaxant property due to general central nervous system depression.
Pregnancy Impact: No Studies Available
Impact During Lactation: No Studies Available
Price of Mobiswift D : Rs.110.50
Diclofenac 50 mg, Metaxalone 400 mg
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