Probable Side Effects: :Bradycardia, hypotension, bronchospasm, cardiac insufficiency, dizziness, tiredness, headache, fatigue, skin rashes, depression, fluid retention, sexual dysfunction.
Drug Interaction: Nebivolol is known to interact with other drugs like chlorthalidone, digoxin, hydrochlorothiazide, theophylline. Always consult your physician for the change of dose regimen or an alternative drug of choice that may strictly be required.
Mechanism of Action: Nebivolol is a selective ?1-receptor antagonist. Activation of ?1-receptors by epinephrine increases the heart rate and the blood pressure, and the heart consumes more oxygen. Nebivolol blocks these receptors which reverses the effects of epinephrine, lowering the heart rate and blood pressure.
Pregnancy Impact: Animal reproduction studies have shown an adverse effect on the fetus and there are no adequate and well-controlled studies in humans, but potential benefits may warrant use of the drug in pregnant women despite potential risks.
Impact During Lactation: Studies in breastfeeding mothers have demonstrated that there is significant and documented risk to the infant based on human experience, or it is a medication that has a high risk of causing significant damage to an infant. The risk of using the drug in breastfeeding women clearly outweighs any possible benefit from breastfeeding. The drug is contraindicated in women who are breastfeeding an infant.
Special Precautions Lactation. May increase frequency and/or severity of angina during treatment initiation or dosage increments. Heart failure or hepatic impairment.
Drug-Interaction rapefruit Juice May Increase Plasma Concentration Of . May Cause Excessive Reduction In Blood Pressure On Interaction With Calcium, Sildenafil, Tadalafil Or Vardenafil. Always Consult Your Physician For The Change Of Dose Regimen Or An Alternative Drug Of Choice That May Strictly Be Required.
Price of Nebicard Sm 10 Tablet : Rs.116.00
Nebivolol 5 mg, S-Amlodipine 2.5 mg
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