Nebistar H contains following Salts:-
Hydrochlorothiazide - Drug Information
Typical usage: :Disorders of calcium balance, Edema, Heart failure, Hypertension, Oedema, and can also be given in adjunctive therapy as an alternative drug of choice in Diabetes insipidus.
Probable Side Effects: :Dizziness, Thirst, Headache, Nausea, Gout, Impotence, Polyuria, Night cramps.
Drug Interaction: None mentioned.
Mechanism of Action: Hydrochlorothiazide, a thiazide diuretic, inhibits water reabsorption in the nephron by inhibiting the sodium-chloride symporter (SLC12A3) in the distal convoluted tubule, which is responsible for 5% of total sodium reabsorption.
Pregnancy Impact: Animal reproduction studies have failed to demonstrate a risk to the fetus and there are no adequate and well-controlled studies in pregnant women.
Impact During Lactation: There are no controlled studies in breastfeeding women, however the risk of untoward effects to a breastfed infant is possible; or, controlled studies show only minimal non-threatening adverse effects. Drugs should be given only if the potential benefit justifies the potential risk to the infant.
Nebivolol - Drug Information
Typical usage: :Essential hypertension, hypertension.
Probable Side Effects: :Bradycardia, hypotension, bronchospasm, cardiac insufficiency, dizziness, tiredness, headache, fatigue, skin rashes, depression, fluid retention, sexual dysfunction.
Drug Interaction: Nebivolol is known to interact with other drugs like chlorthalidone, digoxin, hydrochlorothiazide, theophylline. Always consult your physician for the change of dose regimen or an alternative drug of choice that may strictly be required.
Mechanism of Action: Nebivolol is a selective ?1-receptor antagonist. Activation of ?1-receptors by epinephrine increases the heart rate and the blood pressure, and the heart consumes more oxygen. Nebivolol blocks these receptors which reverses the effects of epinephrine, lowering the heart rate and blood pressure.
Pregnancy Impact: Animal reproduction studies have shown an adverse effect on the fetus and there are no adequate and well-controlled studies in humans, but potential benefits may warrant use of the drug in pregnant women despite potential risks.
Impact During Lactation: Studies in breastfeeding mothers have demonstrated that there is significant and documented risk to the infant based on human experience, or it is a medication that has a high risk of causing significant damage to an infant. The risk of using the drug in breastfeeding women clearly outweighs any possible benefit from breastfeeding. The drug is contraindicated in women who are breastfeeding an infant.
Price of Nebistar H : Rs.85.00
|Dispatches by||Next Day|
|Composition||Hydrochlorothiazide 12.5 mg, Nebivolol 5 mg|
|Salt Information||Hydrochlorothiazide, Nebivolol|
|Brand Name||Lupin Labs|
|Pack Size||10 Tablet|
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Substitutes of Nebistar H
Rs.1.00Cyper Drugs & Pharma
Rs.1.00Orchid Chemicals & Pharma
Rs.1.00Low Cost Standard Therapeutics (Locost)
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