Probable Side Effects: :Flatulence, Dizziness, Vomiting, Constipation, Dry mouth, Blurred vision, Weight gain, Somnolence, Diplopia, Edema, Increased appetite, Abnormal thinking.
Drug Interaction: Concurrent use with oxycodone, lorazepam and ethanol may increase the CNS effects.
Mechanism of Action: Pregabalin is an analog of the neurotransmitter GABA. It binds potently to the alpha2-delta subunit resulting in modulation of Ca channels and reduction in the release of several neurotransmitters, including glutamate, norepinephrine, serotonin, dopamine, and substance P.
Pregnancy Impact: Animal reproduction studies have shown an adverse effect on the fetus and there are no adequate and well-controlled studies in humans, but potential benefits may warrant use of the drug in pregnant women despite potential risks.
Impact During Lactation: Studies in breastfeeding mothers have demonstrated that there is significant and documented risk to the infant based on human experience, or it is a medication that has a high risk of causing significant damage to an infant. The risk of using the drug in breastfeeding women clearly outweighs any possible benefit from breastfeeding. The drug is contraindicated in women who are breastfeeding an infant.
Price of Neugaba (75 Mg) : Rs.103.00
Pregabalin 75 mg
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