Newtain 100Mg injection contains following Salts:-
Protamine Sulfate - Drug Information
Typical usage: :Heparin neutralisation during extracorporeal circulation, Enoxaparin or dalteparin overdosage.
Probable Side Effects: :Hypotension, bradycardia, pulmonary and systemic hypertension, dyspnoea, warm sensation, transitory flushing, nausea and vomiting.
Drug Interaction: None mentioned.
Mechanism of Action: Protamine sulfate, prepared from the sperm or mature testes of salmon or related species, is a heparin antagonist. It combines with heparin to form a stable inactive complex. Protamine sulfate is often used in the treatment of bleeding from severe heparin overdose and should not be used in minor overdose/bleeding as heparin withdrawal will usually correct itself within a few hr. For LMWH, protamine sulfate neutralises the anti-thrombin activity but only partly neutralises the anti-factor-Xa effect.
Pregnancy Impact: Animal reproduction studies have shown an adverse effect on the fetus and there are no adequate and well-controlled studies in humans, but potential benefits may warrant use of the drug in pregnant women despite potential risks.
Impact During Lactation: Studies in breastfeeding mothers have demonstrated that there is significant and documented risk to the infant based on human experience, or it is a medication that has a high risk of causing significant damage to an infant. The risk of using the drug in breastfeeding women clearly outweighs any possible benefit from breastfeeding. The drug is contraindicated in women who are breastfeeding an infant.
Price of Newtain 100Mg injection : Rs.575.00
|Dispatches by||Next Day|
|Composition||Protamine Sulfate 50 mg|
|Salt Information||Protamine Sulfate|
|Brand Name||Chandra Bhagat Pharma|
|Pack Size||1 Unit in Vial|
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Substitutes of Newtain 100Mg injection
Rs.1.00Cyper Drugs & Pharma
Rs.1.00Orchid Chemicals & Pharma
Rs.1.00Low Cost Standard Therapeutics (Locost)
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