Nocold N/F 10Tablet contains following Salts:-
Chlorpheniramine - Drug Information
Typical usage: :For the treatment of rhinitis, urticaria, allergy, common cold, asthma and hay fever.
Probable Side Effects: :Blurred vision, dry eyes, mydriasis, drowsiness, fatigue, headache, dizziness, psychomotor impairment, dry mouth, gastrointestinal disturbances.
Drug Interaction: Avoid excessive alcohol consumption. Anticholinergic effects of chlorphenamine (e.g. dry mouth, blurred vision) may be enhanced by drugs with anticholinergic effects such as antipsychotics, MAOI or tricyclic antidepressants. Chlorphenamine inhibits phenytoin metabolism and can lead to phenytoin toxicity.
Mechanism of Action: Chlorphenamine is an H1-receptor antagonist which competetively blocks H1-receptor sites on tissues.
Pregnancy Impact: Animal reproduction studies have failed to demonstrate a risk to the fetus and there are no adequate and well-controlled studies in pregnant women.
Impact During Lactation: There are no controlled studies in breastfeeding women, however the risk of untoward effects to a breastfed infant is possible; or, controlled studies show only minimal non-threatening adverse effects. Drugs should be given only if the potential benefit justifies the potential risk to the infant.
Phenylephrine - Drug Information
Indications Phenylephrine (HCl) is primarily indicated in conditions like Acid-related dyspepsia, Congestion, Hypotension.
Dosage Adult: PO Nasal congestion As HCl: 10 mg 4 hrly. Max: 60 mg/day. IV Hypotensive states As 0.1% HCl soln: 100-500 mcg via inj, repeat as needed after at least 15 mins. Severe: Infuse 10 mg at initial rate of ?180 mcg/min, then reduce to 30-60 mcg/min according to response. Paroxysmal supraventricular tachycardia As 0.1% HCl soln: Initial max: 500 mcg, may increase subsequent doses by 100-200 mcg, up to 1 mg if needed. IM/SC Hypotensive states As 0.1% HCl soln: Initial: 2-5 mg w/ further doses of 1-10 mg if needed. Rectal Haemorrhoids As cream/oint: Apply ?4 times/day. As supp: Insert 1 supp ?4 times/day. Ophth Mydriasis As HCl: ?10% soln: Instill 1 drop, may repeat in 10-60 mins as needed. Conjunctival decongestant As HCl: Usually 0.12% soln: Instill 1-2 drops ?4 times/day for ?72 hr. Nasal Nasal congestion As 0.25-1% soln: Instill/spray 4 hrly as needed.
Contra-Indications Phenylephrine (HCl) is contraindicated in conditions like Angina,Hypertension,Hyperthyroidism,Myocardial infarction.
Side Effects Difficulty In Breathing, Severe Allergic Reactions, Skin Rash, Urge To Vomit, Feeling Of Being Unwell, Headache, Fast Or Irregular Heartbeat, High Blood Pressure, Restlessness And Difficulty In Passing Urine For Men.
Special Precautions Severe hyperthyroidism, severe ischaemic heart disease, DM, prostatic hyperplasia. Rebound congestion in prolonged or excessive use of nasal drops. Use 10% eye drops in extreme caution in infants, elderly, cardiac disease, significant hypertension, advanced arteriosclerosis. Pregnancy and lactation. Over-the-counter cough and cold medications should not be used in infants and children <2 yr.
Drug-Interaction May increase hypertensive effect of beta-blockers (nonselective); MAOI potentiate hypertension; methyldopa and TCA can increase the pressor response.
Price of Nocold N/F 10Tablet : Rs.25.00
|Dispatches by||Next Day|
|Composition||Chlorpheniramine 8 mg, Phenylephrine 50 mg|
|Salt Information||Chlorpheniramine, Phenylephrine|
|Pack Size||10 Tablet|
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Substitutes of Nocold N/F 10Tablet
Rs.1.00Cyper Drugs & Pharma
Rs.1.00Orchid Chemicals & Pharma
Rs.1.00Low Cost Standard Therapeutics (Locost)
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