P Mute 1000Mg 10Tablet contains following Salts:-
Nabumetone - Drug Information
Indications Nabumetone is primarily indicated in conditions like Endometrial thinning before intra-uterine surgery, Osteoarthritis, Pain, Pain and inflammation in rheumatoid arthritis,Rheumatoid arthritis, and can also be given in adjunctive therapy as an alternative drug of choice in Ankylosing spondylitis, Soft tissue rheumatism.
Dosage Adult: PO 1 g as a single dose in the evening, followed by 0.5-1 g in the morning if needed.
Contra-Indications Active peptic ulceration; severe hepatic impairment; hypersensitivity; patients in whom other NSAIDs or aspirin are likely to induce asthma, angioedema, pruritus or urticaria. Pregnancy (3rd trimester), lactation. Perioperative pain in the setting of CABG
Side Effects Abdominal pain, dyspepsia, diarrhoea, nausea, flatulence, gastritis, vomiting, xerostomia, stomatitis; headache, tinnitus, dizziness; rash, pruritus; constipation; oedema; insomnia, fatigue, nervousness, somnolence; diaphoresis.
Special Precautions Pre-existing CV risk factors or disease; fluid retention, CHF, hypertension. History of GI disease (bleeding or ulcers). Elderly or debilitated patients. Other forms of asthma. Hepatic impairment; closely monitor patients with any abnormal LFT. Renal impairment; rehydrate patient prior to therapy and closely monitor renal function. Withhold for at least 4-6 half-lives prior to surgical or dental procedures.
Drug-Interaction Antihypertensive effects of hypotensive agents may be reduced. May increase ciclosporin levels. Increased risk of seizures with fluoroquinolones. May reduce efficacy of diuretics. May diminish the cardioprotective effect of acetylated salicylates. Alcohol may enhance gastric mucosal irritation. Potentially Fatal: Increased risk of GI ulceration with corticosteroids. May increase lithium levels/toxicity. Severe bone marrow suppression, aplastic anaemia and GI toxicity may occur with methotrexate. Increased risk of bleeding with anticoagulants (e.g. warfarin, heparin, LMWHs) and antiplatelet agents (e.g. ticlopidine, clopidogrel, aspirin, abciximab, dipyridamole, eptifibatide, tirofiban). Absorption may be reduced with colestyramine (and other bile acid sequestrants
Price of P Mute 1000Mg 10Tablet : Rs.131.00
|Dispatches by||Next Day|
|Composition||Nabumetone 1 gm|
|Pack Size||10 Tablet|
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Substitutes of P Mute 1000Mg 10Tablet
Rs.1.00Cyper Drugs & Pharma
Rs.1.00Orchid Chemicals & Pharma
Rs.1.00Low Cost Standard Therapeutics (Locost)
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