Paraflax 10Tablet contains following Salts:-
Chlorzoxazone - Drug Information
Typical usage: :Skeletal muscle spasms.
Probable Side Effects: :Drowsiness, dizziness, lightheadedness, headache, excitement, restlessness.
Drug Interaction: Additive CNS effects when taken with alcohol.
Mechanism of Action: Chlorzoxazone acts at the level of the spinal cord and subcortical areas of the brain where it inhibits multisynaptic areas involved in producing and maintaining skeletal muscle spasm of varied etiology, thus relieving painful musculoskeletal conditions. It also has sedative property.
Pregnancy Impact: Animal reproduction studies have shown an adverse effect on the fetus and there are no adequate and well-controlled studies in humans, but potential benefits may warrant use of the drug in pregnant women despite potential risks.
Impact During Lactation: There are no controlled studies in breastfeeding women, however the risk of untoward effects to a breastfed infant is possible; or, controlled studies show only minimal non-threatening adverse effects. Drugs should be given only if the potential benefit justifies the potential risk to the infant.
Ibuprofen - Drug Information
Indications Ibuprofen is primarily indicated in conditions like Cystic fibrosis, Fever, Juvenile chronic arthritis, Migraine, Mild to moderate pain, Musculoskeletal pain, Nausea and vomiting (palliative care), Osteoarthritis, Pain, Post operative analgesia, Rheumatoid arthritis, Severe pain and tenderness in benign fibrocystic breast disease, Toothache, and can also be given in adjunctive therapy as an alternative drug of choice in Acute arthritis, Ankylosing spondylitis, Dysmenorrhoea, Inflammatory bowel disease.
Dosage Adult: PO Rheumatoid arthritis; Osteoarthritis 400-800 mg 3-4 times/day. Max: 3.2 g/day. Mild to moderate pain; Dysmenorrhoea; Fever 200-400 mg 4-6 hrly. Max: 1.2 g daily. IV Pain relief 400-800 mg 6 hrly, as needed. Max: 3.2 g/day. Fever Initially, 400 mg followed by 400 mg 4-6 hrly, or 100-200 mg 4 hrly. Max: 3.2 g/day. Topical/Cutaneous Pain and inflammation associated w/ musculoskeletal and joint disorders As 5% cream, foam, gel, spray soln or 10% gel: Apply as directed.
Contra-Indications Hypersensitivity. Treatment of perioperative pain in the setting of CABG surgery. Patient whom asthma, urticaria or other allergic-type reaction are precipitated by aspirin or other NSAIDs. Active or history of peptic ulcer; history of GI bleeding. Neonates w/ congenital heart disease, suspected necrotising enterocolitis, and impaired renal function. 3rd trimester of pregnancy, and lactation.
Side Effects Indigestion, Vomiting, Abdominal Pain, Heart Burn, Diarrhea, Dizziness, Skin Rashes, Sever Allergic Reactions. Heart Patients May Experience Swelling Of Body And Fluid Retention. Overdose May Cause Stomach Or Abdominal Pain And Ringing In The Ears
Special Precautions Bleeding disorders, CV disease. Infants w/ increased total bilirubin. Premature neonates w/ existing or at risk of infection. Hepatic and renal impairment. Elderly (avoid chronic use). Monitoring Parameters Monitor CBC, occult blood loss, hepatic and renal function.
Drug-Interaction Increased risk of GI bleeding w/ warfarin, corticosteroids, SSRIs and aspirin. May reduce the natriuretic effects of diuretics. Reduced antihypertensive effect of ACE inhibitors and angiotensin II receptor antagonists. May increase toxicity of lithium and methotrexate. Increased nephrotoxicity w/ ciclosporin and tacrolimus.
Price of Paraflax 10Tablet : Rs.47.00
|Dispatches by||Next Day|
|Composition||Chlorzoxazone 250 mg, Ibuprofen 200 mg|
|Salt Information||Chlorzoxazone, Ibuprofen|
|Brand Name||J & J Chemicals & Pharma|
|Pack Size||10 Tablet|
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Substitutes of Paraflax 10Tablet
Rs.1.00Cyper Drugs & Pharma
Rs.1.00Orchid Chemicals & Pharma
Rs.1.00Low Cost Standard Therapeutics (Locost)
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