Potrate contains following Salts:-
Magnesium Citrate - Drug Information
Potassium Citrate - Drug Information
Typical usage: :Cystitis, gout, kidney stone.
Probable Side Effects: :Allergic reactions, abdominal pain, nausea, vomiting, diarrhea, paralysis.
Drug Interaction: Potassium citrate is known to interact with other drugs like amiloride (HCl), spironolactone, triamterene. Always consult your physician for the change of dose regimen or an alternative drug of choice that may strictly be required.
Mechanism of Action: The metabolism of absorbed citrate produces an alkaline load. The induced alkaline load in turn increases urinary pH and raises urinary citrate by augmenting citrate clearance without measurably altering ultrafilterable serum citrate. Thus, potassium citrate therapy appears to increase urinary citrate principally by modifying the renal handling of citrate, rather than by increasing the filtered load of citrate. The changes induced by potassium citrate tablets produce a urine that is less conducive to the crystallization of stone-forming salts (calcium oxalate, calcium phosphate and uric acid). Increased citrate in the urine, by complexing with calcium, decreases calcium ion activity and thus the saturation of calcium oxalate. Citrate also inhibits the spontaneous nucleation of calcium oxalate and calcium phosphate (brushite).
Pregnancy Impact: Animal reproduction studies have shown an adverse effect on the fetus and there are no adequate and well-controlled studies in humans, but potential benefits may warrant use of the drug in pregnant women despite potential risks.
Impact During Lactation: There are no controlled studies in breastfeeding women, however the risk of untoward effects to a breastfed infant is possible; or, controlled studies show only minimal non-threatening adverse effects. Drugs should be given only if the potential benefit justifies the potential risk to the infant.
Pyridoxine - Drug Information
Typical usage: :Anaemia, Deficiency states, Idiopathic sideroblastic anaemia, Isoniazid neuropathy, Oedema and ascites in cirrhosis of the liver, Premenstrual syndrome, Schizophrenia and other psychoses, Vitamin deficiency.
Probable Side Effects: :Dizziness, Drowsiness, Blurred vision, Pain, Burning.
Drug Interaction: None mentioned.
Mechanism of Action: Vitamin B6 is the collective term for a group of three related compounds, pyridoxine (PN), pyridoxal (PL) and pyridoxamine (PM), and their phosphorylated derivatives, pyridoxine 5'-phosphate (PNP), pyridoxal 5'-phosphate (PLP) and pyridoxamine 5'-phosphate (PMP). Although all six of these compounds should technically be referred to as vitamin B6, the term vitamin B6 is commonly used interchangeably with just one of them, pyridoxine. Vitamin B6, principally in its biologically active coenzyme form pyridoxal 5'-phosphate, is involved in a wide range of biochemical reactions, including the metabolism of amino acids and glycogen, the synthesis of nucleic acids, hemogloblin, sphingomyelin and other sphingolipids, and the synthesis of the neurotransmitters serotonin, dopamine, norepinephrine and gamma-aminobutyric acid (GABA).
Pregnancy Impact: Animal reproduction studies have failed to demonstrate a risk to the fetus and there are no adequate and well-controlled studies in pregnant women.
Impact During Lactation: Drug which has been studied in a limited number of breastfeeding women without an increase in adverse effects in the infant; And/or, the evidence of a demonstrated risk which is likely to follow use of this medication in a breastfeeding woman is remote.
Price of Potrate : Rs.57.00
|Dispatches by||Next Day|
|Composition||Magnesium Citrate 263.1 mg, Potassium Citrate 714.9 mg, Pyridoxine 15 mg|
|Salt Information||Magnesium Citrate, Potassium Citrate, Pyridoxine|
|Brand Name||Intas Laboratories|
|Pack Size||10 Tablet|
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Substitutes of Potrate
Rs.1.00Cyper Drugs & Pharma
Rs.1.00Orchid Chemicals & Pharma
Rs.1.00Low Cost Standard Therapeutics (Locost)
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