Quadriderm Nf (10Gm) contains following Salts:-
Betamethasone - Drug Information
Typical usage: :Replacement therapy: Adrenal insufficiency. Adrenogenital syndrome. Nonendocrine diseases: Rheumatoid arthirits. Osteoarthritis, Acute gouty arthirits. Collagen diseases e.g. systemic lupus erythematosus, polyarteritis nodosa, dermatomyositis, nephritic syndrome, glomerulonephritis and related diseases. Severe allergic reactions e.g. anaphylaxis, angioneurotic edema, urticaria and serum sickness and related diseases. Autoimmune diseases e.g. haemolytic anaemia, idiopathic thrombocytopenic purpura, active chronic hepatitis and related diseases. Other lung diseases e.g. pulmonary edema, accelerate lung maturation and surfactant production in the foetus and prevent respiratory distress syndrome at birth. Infective diseases e.g. severe forms of tuberculosis, severe lepra reaction, certain forms of bacterial meningitis and Pneumocystis carinii pneumonia with hypoxia in AIDS patients along with proper antibiotic cover. Eye diseases e.g. inflammatory ocular diseases, allergic conjunctivitis, iritis, iridocyclitis, keratitis, retinitis, optic neuritis, uveitis. Skin diseases e.g. eczematous skin diseases. Pemphigus vulgaris, exfoliative dermatitis, Stevens Johnson syndrome. Intestinal diseases e.g. ulcerative colitis, Crohns disease, coeliac disease are chronic inflammatory intestinal diseases. Cerebral edema. Malignancies e.g. Acute lymphatic leukaemia, Hodgkins and other lymphomas. Hormone responsive breast carcinoma. Organ transplantation and skin allograft. Septic shock. Thyroid storm.
Probable Side Effects: :Atrophy, steroid purpura, steroid purpura, skin fragility, angioedema, perioral dermatitis, vertigo, headache, diarrhea, fever, anxiety, constipation, abdominal pain, sweating, erythema, hypotension, arthralgia, acne, hypersensitivity reactions, menstrual irregularity, cataract, hypertrichosis, pigmentation, superficial blood vessels dilatation, local hypopigmentation.
Drug Interaction: Betamethasone is known to interact with other drugs like amphotericin B, carbamazepine, lofexidine, metyrosine, oxandrolone, perindopril, phenytoin (Na), rifampicin. Always consult your physician for the change of dose regimen or an alternative drug of choice that may strictly be required.
Mechanism of Action: Betamethasone is a glucocorticoid receptor agonist. This leads to changes in genetic expression once this complex binds to the GRE. The antiinflammatory actions of corticosteroids are thought to involve lipocortins, phospholipase A2 inhibitory proteins which, through inhibits arachidonic acid, control the biosynthesis of prostaglandins and leukotrienes.
Pregnancy Impact: There is positive evidence of human fetal risk based on adverse reaction data from investigational or marketing experience or studies in humans, but potential benefits may warrant use of the drug in pregnant women despite potential risks.
Impact During Lactation: There is positive evidence of risk to a breastfed infant or to breastmilk production, but the benefits of use in breastfeeding mothers may be acceptable despite the risk to the infant (e.g. if the drug is needed in a life-threatening situation or for a serious disease for which safer drugs cannot be used or are ineffective).
Clotrimazole - Drug Information
Typical usage: :Vulvo-vaginal candidiasis, trichomonas vaginitis, non specific vaginitis, mixed vaginal infections. Infective leucorrhoeas. Gram positive and gram negative bacteria. Fungal infections of skin, hair and vagina. Dusting powder for prevention of athelets feet and ringworm of skin folds. Cutaneous candidiasis. Otomycosis, fungal infections of external ear.
Probable Side Effects: :Nausea, vomiting, diarrhea, abdominal cramps, pruritus, sedation, burning, hallucination, depression, polyuria, skin irritation, disorientation, contact dermatitis, elevated serum llipids, elevated alkaline phosphatase, elevated hepatic transaminases, vaginal irritation, GI irritation, vision disturbances.
Drug Interaction: Clotrimazole is known to interact with other drugs like aliskiren. Always consult your physician for the change of dose regimen or an alternative drug of choice that may strictly be required.
Mechanism of Action: Clotrimazole alters the permeability of the fungal cell wall and inhibits the activity of enzymes within the cell. It specifically inhibits the biosynthesis of ergosterol and other sterols required for cell membrane production. Clotrimazole may also inhibit endogenous respiration, interact with membrane phospholipids, inhibit the transformation of yeasts to mycelial forms and the uptake of purine, impair triglyceride and/or phospholipid biosynthesis, and inhibit the movement of calcium and potassium ions across the cell membrane by blocking the ion transport pathway known as the Gardos channel.
Pregnancy Impact: Animal reproduction studies have shown an adverse effect on the fetus and there are no adequate and well-controlled studies in humans, but potential benefits may warrant use of the drug in pregnant women despite potential risks.
Impact During Lactation: There are no controlled studies in breastfeeding women, however the risk of untoward effects to a breastfed infant is possible; or, controlled studies show only minimal non-threatening adverse effects. Drugs should be given only if the potential benefit justifies the potential risk to the infant.
Price of Quadriderm Nf (10Gm) : Rs.54.00
|Dispatches by||Next Day|
|Composition||Betamethasone 0.64 mg, Clotrimazole 1 mg|
|Salt Information||Betamethasone, Clotrimazole|
|Pack Size||10 gm|
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Substitutes of Quadriderm Nf (10Gm)
Rs.1.00Cyper Drugs & Pharma
Rs.1.00Orchid Chemicals & Pharma
Rs.1.00Low Cost Standard Therapeutics (Locost)
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