Rabiplus Xt 10Capsule contains following Salts:-
Rabeprazole - Drug Information
Typical usage: :Benign gastric and peptic ulcer. Erosive of ulcerative gastro-oesophageal reflux disease (GORD). Acid peptic disease.
Probable Side Effects: :Nausea, stomach upset, skin rash, acute toxicity.
Drug Interaction: There have been reports of an increase in the effect of the blood thinner, warfarin (Coumadin), by rabeprazole which theoretically could lead to increased bleeding. Patients taking warfarin should be monitored more frequently if they begin taking rabeprazole. Rabeprazole may reduce the elimination of cyclosporin in the liver, thereby increasing cyclosporin levels in the blood and potentially leading to cyclosporin toxicity. The absorption of certain drugs may be affected by changes in stomach acidity. Rabeprazole and other PPIs that reduce stomach acid reduce the absorption and concentration in blood ofketoconazole (Nizoral) and increase the absorption and concentration in blood of digoxin (Lanoxin). This may lead to reduced effectiveness of ketoconazole or increased digoxin toxicity, respectively. PPIs may decrease blood levels of atazanavir (Reyataz).
Mechanism of Action: Rabeprazole is an oral drug that is used for the treatment of conditions caused by acid. It is in a class of drugs called proton pump inhibitors or PPIs which block the production of acid by the stomach. Other drugs in the same class include lansoprazole (Prevacid),omeprazole (Prilosec), pantoprazole (Protonix), esomeprazole (Nexium), and dexlansoprazole (Dexilant). PPIs are used for the treatment of acid-caused conditions such as stomach and duodenal ulcers, gastroesophageal reflux disease (GERD) and Zollinger-Ellison Syndrome. Rabeprazole, like other PPIs, blocks the pump in the wall of the stomach that secretes acid into the stomach. By blocking the pump, the secretion of acid into the stomach is decreased, and this allows ulcers in the stomach and esophagus to heal. The FDA approved rabeprazole in August 1999.
Pregnancy Impact: Animal reproduction studies have shown an adverse effect on the fetus and there are no adequate and well-controlled studies in humans, but potential benefits may warrant use of the drug in pregnant women despite potential risks.
Impact During Lactation: Studies in breastfeeding mothers have demonstrated that there is significant and documented risk to the infant based on human experience, or it is a medication that has a high risk of causing significant damage to an infant. The risk of using the drug in breastfeeding women clearly outweighs any possible benefit from breastfeeding. The drug is contraindicated in women who are breastfeeding an infant.
Itopride - Drug Information
Typical usage: :Non-ulcer dyspepsia (chronic gastritis) ie, sensation of bloating, early satiety, upper abdominal pain or discomfort, anorexia, heartburn, nausea and vomiting.
Probable Side Effects: :Leukopenia, thrombocytopenia, anaphylactoid reaction, increased prolactin level and gynecomastia, dizziness, headache and tremor, diarrhea, constipation, abdominal pain, increased saliva and nausea, Jaundice, rash, redness and itching.
Drug Interaction: Itopride is known to interact with other drugs like warfarin, diazepam, diclofenac sodium, ticlopidine HCl, nifedipine, nicardipine HCl. Always consult your physician for the change of dose regimen or an alternative drug of choice that may strictly be required.
Mechanism of Action: Itopride has anticholinesterase (AchE) activity as well as dopamine D2 receptor antagonistic activity through dopamine D2 receptor antagonism, removes the inhibitory effects on acetylcholine (Ach) release. It also inhibits the enzyme AchE which prevents the degradation of ACh. The net effect is an increase in ACh concentration, which in turn, promotes gastric motility, increases the lower esophageal sphincter pressure, accelerates gastric emptying and improves gastro-duodenal coordination.
Pregnancy Impact: No Studies Available
Impact During Lactation: No Studies Available
Price of Rabiplus Xt 10Capsule : Rs.146.00
|Dispatches by||Next Day|
|Composition||Itopride 150 mg, Rabeprazole 20 mg|
|Salt Information||Itopride, Rabeprazole|
|Pack Size||10 Capsule|
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Substitutes of Rabiplus Xt 10Capsule
Rs.1.00Cyper Drugs & Pharma
Rs.1.00Orchid Chemicals & Pharma
Rs.1.00Low Cost Standard Therapeutics (Locost)
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