Typical usage: :Potent mucolytic and mucokinetic agent, capable of bringing out bronchial secreation especially mucous plugs. Chronic obstructive lung disease, bronchiectesis.
Probable Side Effects: :Hypersensitivity reactions, contact allergy.
Drug Interaction: Ambroxol is known to interact with other drugs like codeine. Always consult your physician for the change of dose regimen or an alternative drug of choice that may strictly be required.
Mechanism of Action: Ambroxol is a secretolytic agent used in the treatment of respiratory diseases associated with viscid or excessive mucus. It stimulates synthesis and release of surfactant by type IIpneumocytes. Surfactants acts as an anti-glue factor by reducing the adhesion of mucus to the bronchial wall, in improving its transport and in providing protection against infection and irritating agents.
Pregnancy Impact: Animal reproduction studies have shown an adverse effect on the fetus and there are no adequate and well-controlled studies in humans, but potential benefits may warrant use of the drug in pregnant women despite potential risks.
Impact During Lactation: There are no controlled studies in breastfeeding women, however the risk of untoward effects to a breastfed infant is possible; or, controlled studies show only minimal non-threatening adverse effects. Drugs should be given only if the potential benefit justifies the potential risk to the infant.
Drug Interaction: Risk of increased INR and epistaxis when taken together with warfarin. CNS depressants and anticholinergics may potentiate CNS depression of cetirizine.
Mechanism of Action: Cetirizine is a potent and highly selective antagonist of the peripheral histamine H1-receptor on effector cells in the GI tract, blood vessels and respiratory tract.
Pregnancy Impact: Animal reproduction studies have failed to demonstrate a risk to the fetus and there are no adequate and well-controlled studies in pregnant women.
Impact During Lactation: Drug which has been studied in a limited number of breastfeeding women without an increase in adverse effects in the infant; And/or, the evidence of a demonstrated risk which is likely to follow use of this medication in a breastfeeding woman is remote.
Price of Relent Plus Syrup : Rs.57.00
Ambroxol 30 mg/5 ml, Cetirizine 2.5 mg
Dr. Reddy Labs
60 ml in Bottle
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