Probable Side Effects: :Diarrhea and moderate skin rash.
Drug Interaction: Certain medications interact with vitamin B1: Some interactions may increase the need for vitamin B1, other interactions may be negative and indicate vitamin B1 should not be taken without first speaking with your physician or pharmacist, others may require further explanation. Refer to the individual drug article for specific details about an interaction. Note: the following list only includes the generic or class name of a medication. Loop Diuretics (increase the need for vitamin B-1). Oral Contraceptives (increase the need for vitamin B-1). Stavudine (increases the need for vitamin B-1). Tricyclic Antidepressants (increase the need for vitamin B-1)
Mechanism of Action: Benfotiamine exerts it beneficial effects via a number of mechanisms. It is helpful in treating Diabetes in more than one different way.
Pregnancy Impact: Adequate and well-controlled studies have failed to demonstrate a risk to the fetus in the first trimester of pregnancy (and there is no evidence of risk in later trimesters).
Impact During Lactation: Drug which has been taken by a large number of breastfeeding mothers without any observed increase in adverse effects in the infant. Controlled studies in breastfeeding women fail to demonstrate a risk to the infant and the possibility of harm to the breastfeeding infant is remote; or the product is not orally bioavailable in an infant.
Typical usage: :Peripheral neuropathy, megaloblastic anaemia, and as a preliminary treatment for amyotrophic lateral sclerosis.
Probable Side Effects: :Anorexia, nausea, vomiting and diarrhoea, rash, headache, hot sensation, diaphoresis and pain or induration at IM injection site.
Drug Interaction: Methylcobalamin is known to interact with other drugs like neomycin, aminosalicylic acid, H2-blockers and colchicine. Always consult your physician for the change of dose regimen or an alternative drug of choice that may strictly be required.
Mechanism of Action: Methylcobalamin is the neurologically active form of vitamin B12 and occurs as a water-soluble vitamin in the body. It is a cofactor in the enzyme methionine synthase, which functions to transfer methyl groups for the regeneration of methionine from homocysteine. In anaemia, it increases erythrocyte production by promoting nucleic acid synthesis in the bone marrow and by promoting maturation and division of erythrocytes.
Pregnancy Impact: Animal reproduction studies have shown an adverse effect on the fetus and there are no adequate and well-controlled studies in humans, but potential benefits may warrant use of the drug in pregnant women despite potential risks.
Impact During Lactation: There are no controlled studies in breastfeeding women, however the risk of untoward effects to a breastfed infant is possible; or, controlled studies show only minimal non-threatening adverse effects. Drugs should be given only if the potential benefit justifies the potential risk to the infant.
Price of Renerve Plusbt 15Capsule : Rs.224.00
Benfotiamine 150 mg, Mecobalamin 1.5 mg
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