Silverex A 240Gm contains following Salts:-
Chlorhexidine Gluconate - Drug Information
Typical usage: :Abrasion, bladder irrigation, bleeding, burns, cuts, gingivitis, infected cracked skin, minor burns, minor scalds, pleural and peritoneal irrigation, skin infections, skin lesions, sunburn blisters, ulcers, urethral infection.
Probable Side Effects: :Shortness of breadth, hemolysis, hypersensitivity reactions, photophobia, slurred speech, allergic skin reactions, nausea, vomiting, allergic reactions, photosensitivity, skin irritation, skin sensitization, irritation of sensitive tissues, dermatitis, taste disturbances, teeth discoloration.
Drug Interaction: Chlorhexidine is known to interact with other drugs like povidone-iodine. These interactions are sometimes beneficial and sometimes may pose threats to life. Always consult your physician for the change of dose regimen or an alternative drug of choice that may strictly be required.
Mechanism of Action: Chlorhexidine's antimicrobial effects are associated with the attractions between chlorhexidine (cation) and negatively charged bacterial cells. After chlorhexidine is absorpted onto the organism's cell wall, it disrupts the integrity of the cell membrane and causes the leakage of intracellular components of the organisms.
Pregnancy Impact: Animal reproduction studies have shown an adverse effect on the fetus and there are no adequate and well-controlled studies in humans, but potential benefits may warrant use of the drug in pregnant women despite potential risks.
Impact During Lactation: There are no controlled studies in breastfeeding women, however the risk of untoward effects to a breastfed infant is possible; or, controlled studies show only minimal non-threatening adverse effects. Drugs should be given only if the potential benefit justifies the potential risk to the infant.
Silver Sulphadiazine - Drug Information
Typical usage: :Bacterial infections, burns and scalds, infections, wounds.
Probable Side Effects: :Nephrotic syndrome, leucopenia, glomerulonephritis.
Drug Interaction: Silver Sulphadiazine is known to interact with other drugs like povidone-iodine, sulfacetamide sodium, tolbutamide, trimethoprim. Always consult your physician for the change of dose regimen or an alternative drug of choice that may strictly be required.
Mechanism of Action: Silver sulfadiazine acts only on the cell membrane and cell wall to produce its bactericidal effect. Silver ions bind to nucleophilic amino acids, as well as sulfhydryl, amino, imidazole, phosphate, and carboxyl groups in proteins, causing protein denaturation and enzyme inhibition. Silver binds to surface membranes and proteins, causing proton leaks in the membrane, leading to cell death. Sulfadiazine is a competitive inhibitor of bacterial para-aminobenzoic acid (PABA), a substrate of the enzyme dihydropteroate synthetase. The inhibited reaction is necessary in these organisms for the synthesis of folic acid.
Pregnancy Impact: Animal reproduction studies have failed to demonstrate a risk to the fetus and there are no adequate and well-controlled studies in pregnant women.
Impact During Lactation: Studies in breastfeeding mothers have demonstrated that there is significant and documented risk to the infant based on human experience, or it is a medication that has a high risk of causing significant damage to an infant. The risk of using the drug in breastfeeding women clearly outweighs any possible benefit from breastfeeding. The drug is contraindicated in women who are breastfeeding an infant.
Price of Silverex A 240Gm : Rs.295.00
|Dispatches by||Next Day|
|Composition||Chlorhexidine Gluconate 0.2%, Silver Sulphadiazine 1%|
|Salt Information||Chlorhexidine Gluconate, Silver Sulphadiazine|
|Pack Size||240 gm in Tube|
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Substitutes of Silverex A 240Gm
Rs.1.00Cyper Drugs & Pharma
Rs.1.00Orchid Chemicals & Pharma
Rs.1.00Low Cost Standard Therapeutics (Locost)
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