Sorifix 15Gm Ointment contains following Salts:-
Calcipotriol - Drug Information
Typical usage: :Topical treatment of psoriasis.
Probable Side Effects: :Weakness, headache, fatigue, anorexia, abdominal pain, erythema, weight Loss, contact dermatitis, hot flushes, local irritation, facial dermatitis, xerosis.
Drug Interaction: No data regarding the interactions of calcipotriol was found.
Mechanism of Action: The precise mechanism of calcipotriol in remitting psoriasis is not well-understood. However, it has been shown to have comparable affinity with calcitriol for the Vitamin D receptor, while being less than 1% as active as the calcitriol in regulating calcium metabolism. The Vitamin D receptor (VDR) belongs to the steroid/thyroid receptor superfamily, and is found on the cells of many different tissues including the thyroid, bone, kindney, and T cells of the immune system. T cells are known to play a role in psoriasis, and it is thought that the binding of calcipotriol to the VDR modulates the T cells gene transcription of cell differentiation and proliferation related genes.
Pregnancy Impact: Animal reproduction studies have shown an adverse effect on the fetus and there are no adequate and well-controlled studies in humans, but potential benefits may warrant use of the drug in pregnant women despite potential risks.
Impact During Lactation: Studies in breastfeeding mothers have demonstrated that there is significant and documented risk to the infant based on human experience, or it is a medication that has a high risk of causing significant damage to an infant. The risk of using the drug in breastfeeding women clearly outweighs any possible benefit from breastfeeding. The drug is contraindicated in women who are breastfeeding an infant.
Clobetasol Propionate - Drug Information
Price of Sorifix 15Gm Ointment : Rs.297.00
|Dispatches by||Same Day|
|Composition||Calcipotriol 0.005%, Clobetasole Propionate 0.05% w/w|
|Salt Information||Calcipotriol, Clobetasol Propionate|
|Brand Name||La Pristine Bioceutiicals|
|Pack Size||1 Unit|
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Substitutes of Sorifix 15Gm Ointment
Rs.1.00Cyper Drugs & Pharma
Rs.1.00Orchid Chemicals & Pharma
Rs.1.00Low Cost Standard Therapeutics (Locost)
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