Stator R 2.5Mg 10Tablet contains following Salts:-
Atorvastatin - Drug Information
Typical usage: :Familial hypercholesterolaemia, homozygous familial hypercholesterolemia, hypercholesterolaemia, hyperlipoproteinaemia, hypertriglyceridaemia.
Probable Side Effects: :Flatulence, weakness, headache, diarrhea, fever, myalgia, constipation, insomnia, abdominal pain, skin rashes, blurred vision, pharyngitis, dyspepsia, malaise, asthenia, arthralgia, elevation of liver enzymes, myopathy, backache, increased intracranial pressure, GI disturbance, sinusitis.
Drug Interaction: Atorvastatin is known to interact with other drugs like aliskiren, amprenavir, cimetidine (HCl), colestipol (HCl), cyclosporin A, digoxin, erythromycin, mibefradil (Di HCl), nicotinic acid, repaglinide, warfarin (Na). Always consult your physician for the change of dose regimen or an alternative drug of choice that may strictly be required.
Mechanism of Action: Atorvastatin selectively and competitively inhibits the hepatic enzyme HMG-CoA reductase. As HMG-CoA reductase is responsible for converting HMG-CoA to mevalonate in the cholesterol biosynthesis pathway, this results in a subsequent decrease in hepatic cholesterol levels.
Pregnancy Impact: Studies in animals or humans have demonstrated fetal abnormalities and/or there is positive evidence of human fetal risk based on adverse reaction data from investigational or marketing experience, and the risks involved in use of the drug in pregnant women clearly outweigh potential benefits.
Impact During Lactation: Studies in breastfeeding mothers have demonstrated that there is significant and documented risk to the infant based on human experience, or it is a medication that has a high risk of causing significant damage to an infant. The risk of using the drug in breastfeeding women clearly outweighs any possible benefit from breastfeeding. The drug is contraindicated in women who are breastfeeding an infant.
Ramipril - Drug Information
Typical usage: :Benign gastric ulcer associated with H.pylori, Congestive heart failure (adjunct), Gastric acid reduction during anaesthesia, Heart failure, Hypertension, Iron deficiency anaemia, Mild to moderate hypertension, Prophylaxis of cardiovascular events/stroke.
Probable Side Effects: :Dizziness, Headache, Diarrhea, Rashes, Nausea and vomiting.
Drug Interaction: Non steroidal drugs may increase risk of deterioration of renal function.
Mechanism of Action: Ramipril is an ACE inhibitor which is metabolised into the active metabolite ramiprilat. It competitively inhibits angiotensin-converting enzyme (ACE) from converting angiotensin I to angiotensin II resulting in increased plasma renin activity and reduced aldosterone secretion. It also increases bradykinin levels. By these mechanisms, ramipril produces a hypotensive effect and a beneficial effect in CHF.
Pregnancy Impact: There is positive evidence of human fetal risk based on adverse reaction data from investigational or marketing experience or studies in humans, but potential benefits may warrant use of the drug in pregnant women despite potential risks.
Impact During Lactation: There is positive evidence of risk to a breastfed infant or to breastmilk production, but the benefits of use in breastfeeding mothers may be acceptable despite the risk to the infant (e.g. if the drug is needed in a life-threatening situation or for a serious disease for which safer drugs cannot be used or are ineffective).
Price of Stator R 2.5Mg 10Tablet : Rs.41.00
|Dispatches by||Next Day|
|Composition||Atorvastatin 10 mg, Ramipril 2.5 mg|
|Salt Information||Atorvastatin, Ramipril|
|Pack Size||10 Tablet|
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Substitutes of Stator R 2.5Mg 10Tablet
Rs.1.00Cyper Drugs & Pharma
Rs.1.00Orchid Chemicals & Pharma
Rs.1.00Low Cost Standard Therapeutics (Locost)
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