Sucrafil D contains following Salts:-
Domperidone - Drug Information
Typical usage: :Acute nausea and vomiting, dyspepsia, functional dyspepsia, gastric distension pain due to pressure on the stomach, gastro-oesophageal reflux disease, nausea and vomiting, nausea and vomiting (chemotherapy induced), nausea and vomiting (L-dopa induced).
Probable Side Effects: :Tardive dyskinesia, parkinsonism, extrapyramidal dystonic reactions, convulsions, coma, GI disturbances, extrapyramidal effects, thirst, headache, drowsiness, diarrhea, anxiety, restlessness, insomnia, nervousness, skin rashes, dry mouth, itching, galactorrhea, breast enlargement, soreness, hyperprolactinemia.
Drug Interaction: Domperidone is known to interact with other drugs like apomorphine, bromocriptine (Mesylate), cabergoline, cinnarizine, lisuride, oxycodone, pergolide, piribedil. Always consult your physician for the change of dose regimen or an alternative drug of choice that may strictly be required.
Mechanism of Action: Domperidone facilitates gastric emptying and decreases small bowel transit time by increasing esophageal and gastric peristalsis and by lowering esophageal sphincter pressure. Antiemetic: The antiemetic properties of domperidone are related to its dopamine receptor blocking activity at both the chemoreceptor trigger zone and at the gastric level. It has strong affinities for the D2 and D3 dopamine receptors, which are found in the chemoreceptor trigger zone, located just outside the blood brain barrier, which - among others - regulates nausea and vomiting.
Pregnancy Impact: Animal reproduction studies have shown an adverse effect on the fetus and there are no adequate and well-controlled studies in humans, but potential benefits may warrant use of the drug in pregnant women despite potential risks.
Impact During Lactation: There are no controlled studies in breastfeeding women, however the risk of untoward effects to a breastfed infant is possible; or, controlled studies show only minimal non-threatening adverse effects. Drugs should be given only if the potential benefit justifies the potential risk to the infant.
Simethicone - Drug Information
Typical usage: :Esophagitis, flatulence, gastric bloating, gastrocardiac syndrome, irritable bowel syndrome, itchy dermatitis, meteorism, oesophagitis, peptic ulcer, postoperative gas pains.
Probable Side Effects: :Rashes, hives, diarrhea, constipation, itching, burning, heart burn, bloating, stinging.
Drug Interaction: Simethicone is known to interact with other drugs like alginic acid, aluminium hydroxide and oxide, strontium-89 chloride. Always consult your physician for the change of dose regimen or an alternative drug of choice that may strictly be required.
Mechanism of Action: Simethicone releives acidity by lowering the surface tension of gas bubbles.
Pregnancy Impact: No Studies Available
Impact During Lactation: No Studies Available
Sucralfate - Drug Information
Typical usage: :Duodenal and gastric ulcer. Chronic gastritis.
Probable Side Effects: :Not reported so far.
Drug Interaction: When administered with other drugs sucralfate may bind to the drugs in the stomach and reduce absorption of the drugs. Sucralfate reduces the absorption of cimetidine (Tagamet), digoxin(Lanoxin), ketoconazole (Nizoral), levothyroxine (Synthroid), phenytoin(Dilantin), quinidine (Quinidex, Quinaglute), ranitidine (Zantac), tetracycline,theophylline (Theo-Dur, Uniphyl, others), and all of the fluoroquinolone antibiotics, including ciprofloxacin (Cipro), norfloxacin (Noroxin), ofloxacin(Floxin), and lomefloxacin (Maxaquin). All of these medications should be taken at least two hours prior to the sucralfate.
Mechanism of Action: Sucralfate protects GI lining against peptic acid, pepsin and bile salts by binding with positively-charged proteins in exudates forming a viscous paste-like adhesive substance thus forming a protective coating.
Pregnancy Impact: Animal reproduction studies have failed to demonstrate a risk to the fetus and there are no adequate and well-controlled studies in pregnant women.
Impact During Lactation: Drug which has been studied in a limited number of breastfeeding women without an increase in adverse effects in the infant; And/or, the evidence of a demonstrated risk which is likely to follow use of this medication in a breastfeeding woman is remote.
Price of Sucrafil D : Rs.50.00
|Composition||Domperidone 10 mg, Simethicone 25 mg, Sucralfate 500 mg|
|Salt Information||Domperidone, Simethicone, Sucralfate|
|Pack Size||10 Tablet|
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Substitutes of Sucrafil D
Rs.1.00Cyper Drugs & Pharma
Rs.1.00Orchid Chemicals & Pharma
Rs.1.00Low Cost Standard Therapeutics (Locost)
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