Zidovir 300 contains following Salts:-
Zidovudine - Drug Information
Typical usage: :AIDS, HIV infection.
Probable Side Effects: :Polymyositis, encephalitis, anemia, neutropenia, leucopenia, headache, nausea, insomnia.
Drug Interaction: Zidovudine is known to interact with other drugs like acyclovir, aspirin, atovaquone, azapropazone, cimetidine (HCl), clarithromycin, Co-trimoxazole, didanosine, etodolac, fenbufen, fenoprofen, floctafenine, fluconazole, flurbiprofen, fosphenytoin, ganciclovir (Na), indinavir (Sulphate), indomethacin, interferon alpha, ketoconazole, meclofenamic acid, meloxicam, oxaprozin. Always consult your physician for the change of dose regimen or an alternative drug of choice that may strictly be required.
Mechanism of Action: Zidovudin inhibits the activity of HIV-1 reverse transcriptase (RT) via DNA chain termination after incorporation of the nucleotide analogue. It competes with the natural substrate dGTP and incorporates itself into viral DNA. It is also a weak inhibitor of cellular DNA polymerase ? and ?.
Pregnancy Impact: Animal reproduction studies have shown an adverse effect on the fetus and there are no adequate and well-controlled studies in humans, but potential benefits may warrant use of the drug in pregnant women despite potential risks.
Impact During Lactation: Studies in breastfeeding mothers have demonstrated that there is significant and documented risk to the infant based on human experience, or it is a medication that has a high risk of causing significant damage to an infant. The risk of using the drug in breastfeeding women clearly outweighs any possible benefit from breastfeeding. The drug is contraindicated in women who are breastfeeding an infant.
Price of Zidovir 300 : Rs.167.01
|Dispatches by||Same Day|
|Composition||Zidovudine 300 mg|
|Pack Size||1 Tablet|
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Substitutes of Zidovir 300
Rs.1.00Cyper Drugs & Pharma
Rs.1.00Orchid Chemicals & Pharma
Rs.1.00Low Cost Standard Therapeutics (Locost)
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