Zomitc contains following Salts:-
Domperidone - Drug Information
Typical usage: :Acute nausea and vomiting, dyspepsia, functional dyspepsia, gastric distension pain due to pressure on the stomach, gastro-oesophageal reflux disease, nausea and vomiting, nausea and vomiting (chemotherapy induced), nausea and vomiting (L-dopa induced).
Probable Side Effects: :Tardive dyskinesia, parkinsonism, extrapyramidal dystonic reactions, convulsions, coma, GI disturbances, extrapyramidal effects, thirst, headache, drowsiness, diarrhea, anxiety, restlessness, insomnia, nervousness, skin rashes, dry mouth, itching, galactorrhea, breast enlargement, soreness, hyperprolactinemia.
Drug Interaction: Domperidone is known to interact with other drugs like apomorphine, bromocriptine (Mesylate), cabergoline, cinnarizine, lisuride, oxycodone, pergolide, piribedil. Always consult your physician for the change of dose regimen or an alternative drug of choice that may strictly be required.
Mechanism of Action: Domperidone facilitates gastric emptying and decreases small bowel transit time by increasing esophageal and gastric peristalsis and by lowering esophageal sphincter pressure. Antiemetic: The antiemetic properties of domperidone are related to its dopamine receptor blocking activity at both the chemoreceptor trigger zone and at the gastric level. It has strong affinities for the D2 and D3 dopamine receptors, which are found in the chemoreceptor trigger zone, located just outside the blood brain barrier, which - among others - regulates nausea and vomiting.
Pregnancy Impact: Animal reproduction studies have shown an adverse effect on the fetus and there are no adequate and well-controlled studies in humans, but potential benefits may warrant use of the drug in pregnant women despite potential risks.
Impact During Lactation: There are no controlled studies in breastfeeding women, however the risk of untoward effects to a breastfed infant is possible; or, controlled studies show only minimal non-threatening adverse effects. Drugs should be given only if the potential benefit justifies the potential risk to the infant.
Ranitidine - Drug Information
Typical usage: :Benign duodenal and gastric ulcer, Reflux oesophagitis, Acid peptic disease.
Probable Side Effects: :Headache, dizziness. Rarely hepatitis, thrombocytopaenia.
Drug Interaction: Antacids may interfere with absorption. May decrease the GI absorption of ketoconazole.
Mechanism of Action: Ranitidine blocks histamine H2-receptors in the stomach and prevents histamine-mediated gastric acid secretion. It does not affect pepsin secretion, pentagastrin-stimulated factor secretion or serum gastrin.
Pregnancy Impact: Animal reproduction studies have failed to demonstrate a risk to the fetus and there are no adequate and well-controlled studies in pregnant women.
Impact During Lactation: Drug which has been studied in a limited number of breastfeeding women without an increase in adverse effects in the infant; And/or, the evidence of a demonstrated risk which is likely to follow use of this medication in a breastfeeding woman is remote.
Price of Zomitc : Rs.25.00
|Dispatches by||Next Day|
|Composition||Domperidone 10 mg, Ranitidine 150 mg|
|Salt Information||Domperidone, Ranitidine|
|Brand Name||Emcure Pharma|
|Pack Size||10 Tablet|
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Substitutes of Zomitc
Rs.1.00Cyper Drugs & Pharma
Rs.1.00Orchid Chemicals & Pharma
Rs.1.00Low Cost Standard Therapeutics (Locost)
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